2Khan ZP, Ferguson CN, Jones RM. Alpha-2 and imidazoline receptor agonists, Their pharmacology and therapeutic role[J].Anaesthesia, 1999,54(2):146-165.
3Ebert TJ, Hall JE, Barney J A,et al. The effects of increasing plasma concentrations of dexmedetomidine in humans[J]. Anesthesiology, 2000,93 (2) : 382-394.
3Kanaidel M,Fukusakil M,Tamural S,et al.Hemodynamic and catecholamine responses during tracheal intubation using a lightwand device (Trachlight) in elderly patients with hypertension.J Anesth,2003,17(3):161-165.
4Yoo KY,Jeong SW,Kim SJ,et al.Cardiovascular responses to endotracheal intubation in patients with acute and chronic spinal cord injuries.Anesth Analg,2003,97(4):1162-1167.
5Kunisawa T,Nagata O,Nagashima M,et al.Dexmedetomidine suppresses the decrease in blood pressure during anesthetic induction and blunts the cardiovascular response to tracheal intubation,J Clin Anesth,2009,21(3):194-199.
6Adachi YU,Takamatsu I,Watanabe K,et al.Evaluation of the cardiovascular responses to fiberoptic orotracheal intubation with television monitoring:comparison with conventional direct laryngoscopy.J Clin Anesth,2000,12(7):503-508.
7Chrysostomou C,Schmitt CG.Dexmedetomidine:sedation,analgesia and beyond.Expert Opin Drug Metab Toxicol,2008,4(5):619-627.
8Bekker AY,Basile J,Gold M,et al.Dexmedetomidine for awake carotid endarterectomy:efficacy,hemodynamic profile,and side effects.J Neurosurg.Anesthesiol,2004,16(2):126-135.
10Schuttler J, Albrecht S, Breivik H, et al. A comparison of remifentanil and alfentanil in patients undergoing major abdominal surgery. Anaesthesia, 1997, 52: 307-317.
6Groeben H,Mitzner W,Brown RH.Effects of the alpha2-adrenoceptoragonist dexmedetomidine on bronchoconstriction in dogs.Anesthesiology,2004,100:359-363.
7Okada H,Kurita T,Mochizuki T,et al.The cardioprotective effect ofdexmedetomidine on global ischaemia in isolated rat hearts.Resuscitation,2007,74:538-545.
8Al-Zaben KR,Qudaisat IY,Al-Ghanem SM,et al.Intraoperativeadministration of dexmedetomidine reduces the analgesic requirementsfor children undergoing hypospadius surgery.Eur J Anaesthesiol,2010,27:247-252.
9Tobias JD,Berkenbosch JW.Sedation during mechanical ventilation ininfants and children:dexmedetomidine versus midazolam.South MedJ,2004,97:451-455.
10Dere K, Sucullu I, Budak ET, et al. A comparison of dexme- detomidine versus midazolam for sedation pain and hemody- namic control during colonoscopy under conscious sedation [ J]. Eur J Anaesthesio1,2010,27:648-652.
