妊娠合并恶性肿瘤15例临床分析

Pregnancy Accompay with Malignant Tumor-Clincal Analysis of 15 Cases

目的：探讨妊娠合并恶性肿瘤的临床特征及对母婴的影响,以利于早发现、早诊断、早治疗。方法：回顾性分析我院2007年7月至2011年1月妊娠合并恶性肿瘤15例患者的临床资料。结果：妊娠期最常见的恶性肿瘤为白血病（4例）、宫颈癌（2例）。15例中死亡1例,未分娩1例,妊娠早期化疗后行人工流产5例,妊娠中期行依沙吖啶引产2例,剖宫取胎1例,妊娠28周后行剖宫产4例,经阴道分娩1例。胎儿死亡10例,存活5例,新生儿出生体重2160~3700g,未发现畸形。15例产妇1例死亡,6例失访,8例至今存活。结论：妊娠合并恶性肿瘤不易早期发现,漏诊、误诊率高,进展快、预后差,早期诊断是改善恶性肿瘤患者预后的关键因素。临床上应加强对妊娠合并恶性肿瘤的认识,提高早期诊断水平,做到早发现、早诊治。

Objective：To study the clinical character and the effect of pregnancy accompany with malignant tumor on mother and fetus,in order to make early detection,early diagnosis and early treatment.Methods：Fifteen pregnant women accompany with malignant tumor from July 2007 to January 2011 in our Hospital were retrospectively analyzed.Results：Leukemia and cervical cancer were the most frequent malignant tumor during pregnancy.Among them one was dead,one had continue pregnancy,5 underwent artificial abortion after chemotherapy,2 underwent induced abortions by ethacridine at the second trimester,1 had abdominal hysterotomy,4 had caesarean section after 28 gestational weeks,1 was vaginal delivery.There was 5 live births and 10 perineonate death.Neonatal birth weight was from 2160 g to 3700 g,and there was no congenital malformation.1 of 15 cases was dead,6 were lost of follow up,8 were alive up to now.Conclusions：Malignant tumor during pregnancy is hard to be detected in early stage and the missed diagnosis and misdiagnosis rate is high with bad prognosis.Early diagnosis is the key factor to improve the prognosis of pregnant women with malignant tumor.Strengthening recognition of pregnant women with malignant tumor can increase early diagnosis,early detection and early therapy.