丙戊酸镁治疗外伤后癫痫部分性发作51例临床分析

The Magnesium Valproate Used in Treatment of Patients with Epileptic Partial Seizures Caused by Trauma:A Clinical Analysis of 51 Cases

目的观察丙戊酸镁对外伤后癫痫发作的治疗作用。方法 151例外伤后癫痫患者根据发作类型分为A,B,C三组。A组为部分性发作患者,共51例;B组为部分性发作继发全面性发作患者,共50例;C组为全面性发作患者,共50例。根据体重和个体耐受情况给予丙戊酸镁个体化治疗。结果经过治疗,三组显效率有非常显著统计学差异(P<0.01),总有效率有显著统计学差异(P<0.05)。A组治疗效果最好,其后依次是B组和C组。结论癫痫患者应该及时诊断治疗,根据具体情况做到个体化治疗,从而最大程度的改善预后。

Objective To explore the clinical effects of Magnesium Valproate used in 151 cases of patients with epileptic caused by trauma. Methods 151 cases of epileptic patients were divided into group A, B and C according to disease type.Group A （ 51 cases ） was patients of partial seizures ; Group C （ 50 cases ） was patients of generalized seizures ; Group B （ 50 cases ） was patients of generalized seizures caused by partial seizures.Each patient was given individualized therapy according to weight and Tolerance conditions. Results After treatment, excellence rates between 3 groups have very significant differences （ P 〈 0.01 ）, total efficiency rates have significant differences （ P 〈 0.05 ）. Clinical effect from high to low was： A, B, C. Conclusion Patients with epileptic should be diagnosed early and given individualized therapy according to concrete states, to the aim of improving prognosis in best greatest degree.