Computational Screening of Novel Mitogen-activated Protein Kinase Kinase-1 （MEK1） Inhibitors by Docking and Scoring
Computational Screening of Novel Mitogen-activated Protein Kinase Kinase-1 （MEK1） Inhibitors by Docking and Scoring
参考文献13
-
1S. Han, V. Zhou, S. Pan, Y. Liu, M. Homsby, D. McMuUan, et al., Identification of coumarin derivatives as a novel class of allosteric MEK1 inhibitors, Bioorg Med Chem Lett 15 (2005) 5467-5473.
-
2A. White, C.A. Pargellis, J.M. Studts, B.G. Werneburg, B.T. Farmer, Molecular basis of MAPK-activated protein kinase 2:p38 assembly, Proc. Natl. Acad. Sci. 104 (2007) 6353-6358.
-
3G. Koh, H.F. Teong, M.V. Clement, D. Hsu, P.S. Thiagarajan, A decompositional approach to parameter estimation in pathway modeling: A case study of the Akt and MAPK pathways and their crosstalk, Bioinformatics 22 (2006) e271-280.
-
4J.F. Ohren, H. Chen, A. Pavlovsky, C. Whitehead, E.Zhang, P. Kuffa, et al., Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition, Nat. Struct. Mol. Biol. 11 (2004) 1192-1197.
-
5E. Burgermeister, R. Seger, PPARgamma and MEK interactions in cancer, PPAR Res., Published online in June 26, 2008, doi: 10.1155/2008/309469.
-
6B. Errede, R.M. Cade, B.M. Yashar, Y. Kamada, D.E. Levin, K. Irie, et al., Dynamics and organization of MAP kinase signal pathways, Mol. Reprod. Dev. 42 (1995) 477-485.
-
7T. Nakakuki, N. Yumoto, T. Naka, M. Shirouzu, S. Yokoyama, M. Hatakeyama, Topological analysis of MAPK cascade for kinetic ErbB signaling, PLoS One 3 (2008) e1782.
-
8A. Yacoub, D. Gilfor, W. Hawkins, M.A. Park, D. Hanna, M.P. Hagan, et al., MEKI/2 inhibition promotes Taxotere lethality in mammary tumors in vivo, Cancer Biol. Ther. 5 (2006) 1332-1339.
-
9C.V. Varaprasad, D. Barawkar, E.H. Abdellaoui, S. Chakravarty, M. Allan, H. Chen, et al., Discovery of 3-hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles as potent MEKI inhibitors, Bioorg. Med. Chem. Lett. 16 (2006) 3975-3980.
-
10E.H. Abdellaoui, C.V. Varaprasad, D. Barawkar, S. Chakravarty, A. Maderna, R. Tam, et al., Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors, Bioorg. Med. Chem. Lett. 16 (2006) 5561-5566.
-
1乔静.计算机辅助全新药物分子设计的研究[J].内江科技,2008,29(7):96-97. 被引量：2
-
2刘景陶,刘映雪.计算机辅助药物设计在分子对接中的应用[J].科技创新与应用,2016,6(34):67-67. 被引量：7
-
3Xue Bai,Bo Yu,Hong Su,Junfeng Du,Qiang Yuan.MEK1在结直肠癌中表达及临床意义的研究(英文)[J].The Chinese-German Journal of Clinical Oncology,2012,11(3):142-145.
-
4Jiansheng Li,Ke Liu,Xinke Yang,Jianfeng Gao,Youlong Zhou,Yuewu Zhao,Zhengguo Liu,Jingxia Liu.Age-related changes in cerebral angiogenesis and fetal liver kinase-1 expression after cerebral ischemia/reperfusion[J].Neural Regeneration Research,2010,5(17):1313-1318.
-
5乔静.血管紧张素转换酶抑制剂的分子设计[J].生物技术通讯,2006,17(5):744-746.
-
6组蛋白去乙酰化酶抑制剂：阻滞肿瘤细胞生长[J].广东科技,2010,19(13):72-72.
-
7许顺江,丛斌.PKCζ激活机制及其功能[J].生理科学进展,2005,36(4):309-313. 被引量：4
-
8Po-Yuan Chen,Hong-Jye Hong,Mien-De Jhuo,Tzu-Ching Shih,Yu-Chi Wu,Chia-Hsing Cheng,Yen-YuHuang,Tzu-Hurng Cheng.Old Drug for New Use： Searching for MEK1 （Mitogen- Activated Protein Kinase Kinase 1） Inhibitor by the Computer Aided Drug Design[J].Journal of Life Sciences,2013,7(5):453-458.
-
9沈晗,彭芳芳,张百芳,吴少波,李宪奎,杞少华,武栋成.pEGFP-MEK1/Q56P重组质粒的构建及融合基因在293T细胞中的表达[J].武汉大学学报（理学版）,2004,50(6):751-755.
-
10黄益,王江煌,于暕辰,高晓霞,袁洁.microRNA化学小分子抑制剂的研究进展[J].中国科学：生命科学,2016,46(12):1354-1369.
