桂枝茯苓方物质基础及其制剂质量控制模式研究进展

Study of Material Basis and Quality Control Mode for Guizhi Fuling Fang

探索建立新的中药复方质量控制与评价模式。通过分析现行中药质量控制模式的局限性,以桂枝茯苓方为研究对象,查阅相关文献,对其物质基础的研究进展进行介绍。中药复方是中医用药的主要形式,其物质基础是关键问题之一,也是质量控制的基础。桂枝茯苓方诸药合用,在治疗妇科疾病中起活血化瘀、消肿散结之功效,其痛经的物质基础研究有了一定的进步。然而,桂枝茯苓方治疗相关妇科血瘀疾病的物质基础研究并不完善,且随着现代中药制剂的发展,质量控制也成为关键问题。桂枝茯苓方的物质基础及其制剂质量控制取得一定的进展,提出基于"组分结构理论"的中药复方"组分结构"质量控制模式,以期为深入研究桂枝茯苓方提供科学依据。

To explore the establishment of new quality control and evaluation of traditional Chinese medicine model.By analyzing the current limitations of traditional Chinese medicine quality control model,Guizhifuling Fangwas selected as the internal reference substance,to review the material basis of their progress.Chinese herbal compound is the main form of the treatment of Chinese medicine,the material base is one of the key issues and the basis for quality control.Guizhifuling Fang of various drugs in the treatment of gynecological diseases from promoting blood circulation by removing blood stasis,reducing swelling of the effect,the material basis of their dysmenorrhea have some progresses.However,the research of the material basis of Guizhifuling Fang in treatment-related gynecological blood stasis diseases is not perfect.With the development of modern traditional Chinese medicine preparation,quality control has become a key issue.This review synthesized the relevant literatures of Guizhifuling Fang and summarized the research progress of it and its preparation of quality control material basis.Then put forward the traditional Chinese medicine ＂component structure＂ of quality control model based on the ＂component structure theory ＂ to support a scientific basis for the in-depth study of Guizhifuling Fang branches.