制备鸟苷三醇的新方法

Synthesis of Guanosine Trialcohol

探讨了两种性质相反的聚合物支载的高碘酸根离子和硼氢根离子，以鸟苷为底物，一锅法合成鸟苷三醇，此方法具有操作简便，反应条件温和，合成路线缩短，无须分离中间体，产率较高等特点．

Reacting guanosine with two agtagonist polymeric reagents of P-IO4 and P-BH4 in an onepot gave the title compound has simple orperation, mild reaction condition, and need notisolate the intermediate with higher yield.