钬激光治疗浅表性膀胱癌的疗效

Treatment of superficial bladder cancer with transurethral holmium laser resection

目的比较经尿道钬激光和电切术治疗浅表性膀胱癌的疗效。方法将112例浅表性膀胱癌患者根据治疗方法分为HOLBT（钬激光膀胱肿瘤切除术）组90例和TURBT（经尿道膀胱肿瘤电切术）组22例，比较两组术中、术后情况。结果HOLBT组术中膀胱穿孔的发生率、术后留置尿管天数、住院天数及术后尿路感染的发生率明显低于TURBT组，但两组的平均手术时间、术中输血及术后尿路狭窄的发生率比较差异无统计学意义；HOLBT组与TURBT组术后2年复发率比较差异无统计学意义，但HOLBT组术后5年复发率明显低于TURBT组。结论钬激光是一种理想的治疗浅表性膀胱肿瘤的方法，其术中及术后并发症少，术后恢复时间较短，复发率低。

Objective To compare the therapeutic effect between holmium laser ant standard transurethral resection on superficial bladder cancer. Methods One hundred and twelve patients were divided into holmium laser resection of bladder cancer （HOLBT） group 90 cases and transurethral resection of bladder tumor （TURBT） group 22 cases, according to surgical procedure. The intraoperatvie and postoperative status were compared between both groups. Results The vesical perforation rate, numbers of blood transfusion, catheterization time, hospital stay and urinary tract infection rate were significantly lower in HOLBT group than that in TURBT group. There was no difference in mean operative time, blood transfusion and urinary tract stenosis between the two groups. The 5 -year recurrence rate was lower in HOLBT group than that in TURBT group. Conclusions Holmium laser is a safe, effective alternative in treating superficial bladder cancer, which has fewer complication and recovering time, fast recovery and lower recurrence rate.