542例乳腺手术患者围术期抗菌药物应用调查分析

Investigation and Analysis of the Perioperative Application of Antibiotics in 542 Patients Undergoing Breast Surgery

目的:了解我院乳腺手术患者围术期抗菌药物的临床应用情况。方法:采用回顾性方法,对我院2009年7月-2010年6月542例乳腺手术患者的一般情况、抗菌药物应用情况进行统计、分析。结果:我院乳腺手术患者抗菌药物应用率达90.41%;使用频次较高的依次为第1代头孢菌素、非典型β-内酰胺类、喹诺酮类药;抗菌药物平均费用为413.60元,抗菌药物费用占药品总费用的比例平均为29.04%,占住院总费用的比例平均为8.72%。结论:我院乳腺手术患者围术期抗菌药物应用基本合理,但仍存在一些不足,需引起重视。

OBJECTIVE：To investigate the perioperative application of antibiotics in patients undergoing breast surgery in our hospital. METHODS： By retrospective method, general information of 542 patients undergoing breast surgery from Jul. 2009 to Jun. 2010 and utilization of antibiotics were analyzed statistically. RESULTS： 90.41% of patients undergoing breast surgery in our hospital were given antibiotics. First-generation cephalosporins antimicrobials was used most frequently, followed by atypical β-lactams and quinolones. The average cost of antibiotics was 413.60 yuan, accounting for 29.04% of total drug cost and 8.72% of total hospitalized-expense. CONCLUSION： On the whole, the perioperative application of antibiotics is rational, while there still are some deficiencies which should be paid attention to.