外伤性眼内炎发病危险因素分析

Risk Factors for post-traumatic endophthalmitis

目的探讨影响开放性眼外伤眼内炎发生的危险因素，从而减少眼内炎发生的几率。方法收集2003年1月至2010年5月治疗的开放性眼外伤患者住院病例资料，建立数据库，运用多因素非条件Logistic回归分析方法分析开放性眼外伤后眼内炎发生的独立危险因素。结果共有434例开放性眼外伤病人人选，其中30例发生眼内炎，外伤后眼内炎的发生率为6．9％。在多因素的Logistic回归模型中发现：伤口污染、损伤部位累及前后节、伴有晶状体囊袋破裂并在修补时行晶状体摘除者是眼内炎发生的独立危险因素（P〈0．05）。结论污染伤口、前后节损伤、晶状体囊袋破裂在首次创口修补时行晶状体摘除是外伤后眼内炎发生的独立危险因素。

Objective To determine the risk factors for post-traumatic endophthalmitis. Methods A consecutive retrospective study of patients with open globe injury between Jan 2003 and May 2010was undertaken. Patients with post-traumatic endophthalmitis were identified and added to an endoph-thalmitis database. Any association between those parameters and the subsequent development of endophthalmitis was investigated by multiple logistic regression analysis. Results There were 434 patients were included in the study, 30 patients who developed clinically significant endophthalmitis. The frequency of endophthalmitis after open globe injury was 6.9%. Risk factors identified after multivariate analysis was dirty injury, area of injury on eye include both anterior and posterior segment, lensectomy at the time of primary repair. Conclusions Dirty injury, area of injury on eye include both anterior and posterior segment, lensectomy at the time of primary repair are each independently associated with the development of post-traumatic endophthalmitis.