卵巢成熟性畸胎瘤273例临床分析

Ovarian Mature Cystic Teratoma With Malignant: Study of 273 Cases

目的对卵巢成熟性囊性畸胎瘤的临床特点进行分析。方法回顾性分析2002-07/2007-07在绵阳市中心医院首诊并行手术治疗的卵巢畸胎瘤273例,其中卵巢畸胎瘤恶变2例,对其临床特点进行分析。结果卵巢成熟性囊性畸胎瘤好发于生育年龄,以单侧肿瘤多见（81.3%）,右侧略多于左侧（44.85%和36.44%）,其恶性变很罕见,恶变率为2%~4%,多发生于40岁以后,多为绝经后女性。两类肿瘤中CA199均有较高的阳性率,术前测定CA199作为二者的鉴别指标可能意义不大。结论要加强对妇女的妇科检查,对于40岁以上妇女的卵巢成熟性囊性畸胎瘤,肿瘤体积偏大的,应警惕其恶变的可能。卵巢成熟性畸胎瘤预后较差。

Objective To analyze the clinical characteristics of ovarian mature cystic teratoma with malignant.Methods A total of 273 cases with ovarian mature cystic teratoma,in which 2 cases had malignant change,first visited and underwent gurgical treatment during July,2002 to July,2007 in the Central Hospital of Mianyang were retrospectively reviewed and analyzed the clinical feathures.Results Ovarian mature cystic teratoma occured mainly in female at procreting age,unilateral tumor was more common,accounting for 81.3% of the incidence,and right side（44.85%） was slightly higher than left（36.44%）.Malignant change was merely about 2%-4%,mainly occurred in the people aged above 40 and menopause females.CA199 in two types of tumors had high positive rate,so that CA199 was not a good preoperative determination indicator of the differentiation.Conclusion The routine pelvic examination of woman should be strengthened.For ovarian mature cystic teratoma in women over 40 years,the tumor volume is relatively larger,should be alerted to the possibility of malignant change.The prognosis of ovarian teratoma is poor.