阴道毛滴虫分子致病机制的研究进展

Research Progress on the Molecular Pathogenesis of Trichomonas vaginalis

阴道毛滴虫是一种常见的寄生原虫,以性传播为主。近年来对阴道毛滴虫致病机制的研究日益受到重视,本文从黏附因子、纤黏连蛋白、层黏连蛋白、G蛋白、成孔蛋白、蛋白酶和细胞骨架等方面综述阴道毛滴虫的分子致病机制。

Trichomonas vaginalis is one of the most common human sexually transmitted pathogens that colonize the urogenital mucosa.This paper reviews those factors in the molecular pathogenesis of the parasite,including cell adhesin,interaction with fibronectin and laminin,G-proteins,pore-forming ptotein and proteinases.