纳米磷酸钙骨组织工程支架材料研究进展

A review of nanocrystalline calcium phosphate scaffold in bone tissue engineering

随着纳米和生物技术的进步,国内外学者制备了一系列新型的骨组织工程支架材料。为了更好地认识纳米生物材料的优点和指导制备新型的骨组织工程支架材料,综述了近年来纳米磷酸钙相关支架材料研究进展,着重介绍了纳米磷酸钙陶瓷、纳米磷酸钙复合陶瓷以及纳米磷酸钙/聚合物复合材料制备方法、性能和应用,并总结了各类方法的不足之处和将来发展的趋势。

With the development of nanotechnology and biotechnology, many experts have fabricated a serial of novel bone scaffolds. To better understand the advantages of nano biomaterials and guide the preparation of no- vel bone materials, this review presents the recent advances of nanocrystalline calcium phosphate-related bone scaffold, especially on the preparation method, properties and application of nano calcium phosphate ceramics, calcium phosphate composite ceramics and nano calcium phosphate/polymers composite, and summary the shortcomings and research direction of these methods.