1617例慢性过敏患者食物不耐受检测

Analysis of Food Intolerance Test in 1617 Chronic Allergic Patients

探讨慢性过敏患者食物不耐受特异性抗体分布的临床特征及检测意义。用酶联免疫方法对北京地区1617例慢性过敏患者进行食物不耐受IgG抗体检测,并对其中100例检测阳性者进行IgE抗体检测,随后对检出食物特异性IgG阳性的539例患者进行饮食指导并随访3个月。1617例患者中1407例对1~6种不等的食物特异性IgG升高,阳性率为87.0%。100例IgG阳性患者中IgE阳性率为12%。饮食调整治疗有效率为80.6%。实验表明,食物不耐受可能是某些慢性过敏性疾病的致病因素之一;食物不耐受IgG抗体与IgE抗体无相关性;随访发现,根据食物不耐受检测结果调整饮食可明显改善预后。

To explore the clinical features and significance of the food intolerance specific antibody test in chronic allergic patients.Food allergen-specific IgG were detected by ELISA in 1617 chronic allergic patients,then IgE were detected in 100 specific IgG positive patients.Elimination diet based on food-specific IgG test results was given to 539 patients.These patients were followed up for 3 months to be investigated the effect of eliminating the foods identified by the test.The results showed that the food specific IgG were higher in 1407 individuals than that of controls from 1 to 6 kinds of food with the positive rate of 87.0%.The positive ratio of IgE was 12% in 100 specific IgG positive patients.The effective power was 80.6% with food adjustment.Food intolerance may be one of the etiological factors leading to chronic allergic disease.There was no correlation between Food-specific IgG and IgE antibody.The dietary advice is an effective aid to manage the symptoms of a range of chronic medical conditions.