烧伤创面病原菌定植及其危险因素

Pathogen colonization and risk factors of burn wounds

目的分析烧伤后不同时期创面病原菌定植情况及影响定植的危险因素。方法采集131例烧伤患者不同时期的创面分泌物标本进行细菌培养,对其相关资料采用回顾性调查方法,分析伤后各时期细菌定植情况及影响定植的危险因素。结果烧伤后第3、7、14天,创面细菌定植阳性率逐渐上升,分别为26.72%、61.32%、89.83%,差异具有统计学意义(x^2=71.02,P=0.00)。病区环境、年龄、创面用药、抗菌药物联用、烧伤深度、烧伤类型6方面因素在不同时期对病原菌在创面定植的影响具有统计学意义(均P<0.05)。结论烧伤后创面病原菌定植率不断增高,多重耐药菌不断增多;对烧伤患者分区管理,合理用药,积极处理创面,严格执行消毒隔离措施,积极预防感染的发生至关重要。

Objective To analyze the pathogen colonization and risk factors of burn wounds in different periods. Methods Excretion of burn wounds in 131 patients were performed bacterial culture in different periods , relevant data were surveyed retrospectively, pathogen colonization and influencing factors were analyzed. Results The pathogen colonization rate increased gradually at the 3rd, 7th, 14th day after burn , which was 26. 72%,61.32% and 89. 93% respectively, there were significant difference （22 = 71.02, P〈0. 00）, the influence of six risk factors on the pathogen colonization had statistical significance , including unit environment,patients＇ age, drug application at wound,combination use of antimicrobial agents , depth and types of burn（all P〈0. 05）. Conclusion The pathogen colonization rate , multiple drug-resistant pathogen constantly increase after burn, it＇s very important to prevent burn wound infection by division management for burn patients, rational use of drug , active treatment of wounds, and strict executing of disinfection and isolation measures.