重度颅脑损伤急性期高血糖反应与预后的相关性分析

Dependability analysis of hyperglycosemia and prognosis of patients with severe craniocerebral trauma

目的观察重度颅脑损伤患者急性期血糖浓度的变化规律,分析其与病情严重程度及预后的相关性。方法 78例重度颅脑损伤患者入院后24h内进行格拉斯哥昏迷量表评分和血糖检测,3个月后接受格拉斯哥预后量表评分。结果颅脑损伤后24h的空腹血糖水平显著高于正常值(P<0.05),与格拉斯哥昏迷量表评分呈显著负相关(P<0.05),与患者的预后呈显著负相关(P<0.05)。结论重度颅脑外伤患者急性期的血糖浓度是判断颅脑损伤的严重程度及近期预后的参考指标。

[Objective] To study the associability about blood glucose concentration,degree of disease and prognosis of patients with severe craniocerebral trauma.[Methods] To evaluate 78 severe craniocerebral trauma patients with Glasgow coma scale（GCS） coma scale and blood sugar in 24 hours,and evaluate their prognosis with GCS prognosis scale after 3 months.[Results] The level of serum glucose on severe craniocerebral trauma patients is higher than normal level significantly in 24 hours.There was significantly negative correlation between the level of serum glucose and GCS coma score（P 0.05） and prognosis after 3 months（P 0.05） on severe craniocerebral trauma patients.[Conclusion] The level of serum glucose is associated with the severity of injury and prognosis severity of injury and prognosis of patients.Hyperglycemia indicates serious disease.The level of serum glucose is a significant indicator on severity head injury,and a reliable predictor of prognosis.