碘与大骨节病的关系

Study on the Retations Between Kashin-Beck Disease and iodine

通过对甘肃省大骨节病和碘缺乏病地理分布的调查，探讨了碘与大骨节病之间存在的关系。结果显示大骨节病一般流行于碘缺乏病重病区，两病呈共存状况。病区补硒并实现持续性补碘后，大骨节病病情下降显著。对病区水、粮硒和碘含量及７～１２岁儿童发硒、尿碘、血清Ｔ３、Ｔ４、ＴＳＨ进行了测定，表明大骨节病病区为低硒、低碘环境，病区儿童甲状腺激素水平明显高于非病区，认为大骨节病与缺碘的关系值得进一步研究。

After evatuting the selenium and iodine status in the water and grain from thearea with Kashin-Beck Disease (KBD) as well as hair selenium, urinary iodine, T,.T. andTSH date from the children at the age of 7-12, we find that selenium and iodine are absentin the area with KBD' The incidence of KBD obviously come down with selenium and iodineregularly supplied for a long time. The investigation of the geographic distribution of KBDand IDD in Gansu Province of China shows that KBD usually occurrs in the area where IDDis very severe. As KBD and IDD take on a tendency of coexist in the same area. We hold theopinion that KBD might be related with iodine deficiency'