IL-35研究进展

Progress of IL-35 studies

细胞因子在介导机体针对病原微生物的免疫反应、自身免疫耐受以及维持机体内环境平衡等过程中起了重要作用,IL-35是最近几年新发现的细胞因子,属于IL-12细胞因子家族,对免疫系统和免疫反应有负向抑制作用。本文对这一新细胞因子生物学特性的研究现状作一综述。

Cytokines play an important role in mediating the body＇s immune response to pathogenic microorganisms,maintaining tolerance to self-antigens and the immunological balance of the body.A newly identified cytokine,IL-35,is one of the IL-12 cytokine family,and has inhibitive effects on immune system and immune responses.In this review,the recent studies on the biological characteristics of IL-35 are briefly reviewed.