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HBV对树突状细胞的作用导致乙肝慢性化 被引量:1

Interaction between DC and HBV causes the chronicity of hepatitis B
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摘要 近年来,对于HBV与DC间的作用机制有了一系列的进展,作为免疫系统的哨兵,DC在抗HBV免疫的产生中具有重要意义。HBV感染期间,DC在功能上发生了改变,HBV即通过改变DC功能逃避天然和固有免疫。在这篇综述中,我们突出了HBV与DC间相互作用的具体机制,以进一步阐明乙肝慢性化的原因。 Recent years,researchers have achieved a serious of progress in the mechanisms of interaction between HBV and dendritic cells(DCs).As a sentinel of the immune system,DC is crucial for the generation of protective anti-HBV immunity.During persistent infections with HBV,DC's functional changes help the virus to evade innate and adaptive immunity.In this review,we highlight the detailed mechanisms underlying the outcome of chronic hepatitis B.
出处 《免疫学杂志》 CAS CSCD 北大核心 2011年第7期639-641,644,共4页 Immunological Journal
关键词 HBV DC 乙肝 慢性化 免疫 Hepatitis B virus Dendritic cell Hepatitis B Chronicity Immunity
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