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类风湿关节炎患者高迁移率族蛋白1的检测及临床意义 被引量：2

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摘要 类风湿关节炎（rheumatoid arthritis,RA）是一种以慢性关节滑膜炎症为主要特征的自身免疫性疾病,其发病机制非常复杂,大量细胞因子参与了RA的致病过程。
作者 殷春兰 黄新翔 王俊祥 魏平
机构地区 河北医科大学第三医院免疫风湿科
出处 《北京医学》 CAS 2011年第7期551-551,554,共2页 Beijing Medical Journal
基金 河北省医学科学研究重点课题计划项目(08321)
关键词 类风湿关节炎 高迁移率族蛋白1 关节炎患者 临床意义 自身免疫性疾病 检测 关节滑膜炎症 发病机制
分类号 R593.22 [医药卫生—内科学]
  • 相关文献

参考文献4

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二级参考文献25

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共引文献4

同被引文献29

  • 1郑毅,董馨,陆江阳,赵敏.类风湿关节炎滑膜中高迁移率族蛋白1的表达[J].中华风湿病学杂志,2005,9(11):684-686. 被引量：6
  • 2续洁琨,栗原博,郑洁静,江涛,姚新生.丹参酮类化合物对小鼠应激性肝损伤的保护作用[J].药学学报,2006,41(7):631-635. 被引量：24
  • 3左晓霞,周亚欧,龚艳晖,王彦平,唐道林,肖献忠.类风湿关节炎患者外周血高迁移率族蛋白1表达[J].中华内科杂志,2007,46(7):547-550. 被引量：8
  • 4LI J, KOKKOLA R, TABIBZADEH S, et al. Structural basis for the proinflammatory cytokine activity of high mobility group box 1 [J]. Mol Med,2003,9(12) :37-45.
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  • 6YOUN J H, SHIN J S. Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secre- tion[ J ]. J Immunol,2006,177 ( 11 ) :7889-7897.
  • 7HARABA R, SUICA V I, UYY E, et al. Hyperlipidemia stimu- lates the extracellular release of the nuclear high mobility group box 1 protein [ J ]. Cell Tissue Res ,2011,346 (3) :361- 368.
  • 8HE Z, SHOTORBANI S S, JIAO Z, et al. HMGB1 promotes the differentiation of Thl7 via up-regulating TLR2 and IL-23 of CD14 + monocytes from patients with rheumatoid arthritis [ J ]. Scand J Immuno1,2012,76(5 ) :483-490.
  • 9PARK S Y,LEE S W,KIM H Y,et al. HMGB1 induces an- giogenesis in rheumatoid arthritis via HIF-let activation [ J ]. Eur J Immunol,2014,In Print.
  • 10KIM H Y,PARK S Y,LEE S W,et al. Inhibition of HMGBI- induced angiogenesis by cilostazol via SIRT1 activation in synovial fibroblasts from rheumatoid arthritis [ J ]. 2014,9 (8) :e104743.

引证文献2

二级引证文献16

北京医学
2011年 第7期

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