2Khuri FR,Nemunaitis J,Ganly I,et al. a controlled trial of intratumoral ONYX-015,a selectively-replicating adenovirus,in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer [J]. Nat Med,2000,6(8):879- 885.
3Heise C,Lemmon M,Kirn D. Efficacy with a replication-selective adenovirus plus cisplatin-based chemotherapy:dependence on sequencing but not p53 functional status or route of administration [J]. Clin Cancer Res,2000,6(12):4908- 4914.
4Chang JY,Xia W,Shao R,et al. Inhibition of intratracheal lung cancer development by systemic delivery of E1A [J]. Oncogene,1996,13(7):1405- 1412.
5Frisch SM,Dolter KE.Adenovirus E1a-mediated tumor suppression by a c-erbB-2/neu-independent mechanism [J]. Cancer Res,1995,55(23):5551- 5555.
6Sanchez-Prieto R,Quintanilla M,Cano A,et al. Carcinoma cell lines become sensitive to DNA-damaging agents by the expression of the adenovirus E1A gene [J]. Oncogene,1996,13(5):1083- 1092.
7Steeg PS,Bevilacqua G,Pozzatti R,et al. Altered expression of NM23,a gene associated with low tumor metastatic potential,during adenovirus 2 Ela inhibition of experimental metastasis [J]. Cancer Res,1988, 48(22):6550- 6554.
8Karunagaran,Inhibition of nuclear factor-KB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis [J]. J Biol Chem,1997,272(272):32739- 32742.
9Chinnadurai G. Adenovirus E1a as a tumor-suppressor gene [J]. Oncogene,1992,7(7):1255- 1258.
10Todryk S,Melcher AA,Hardwick N,et al. Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake [J]. J Immunol,1999,163(3):1398- 1408.