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右美托咪定和咪达唑仑用于清醒插管患者镇静的效果比较 被引量:49

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摘要 目的:比较右美托咪定和咪达唑仑用于患者清醒气管插管镇静的效果。方法:口腔外科颌面部骨折的患者60例,平均分为两组:D组静脉输注右美托咪定0.6μg/kg,M组静脉输注咪达唑仑0.08mg/kg,均用生理盐水10mL稀释,10min输注完毕。在2%丁卡因表面麻醉下行纤支镜清醒鼻腔插管,观察患者血流动力学指标及呼吸指标的变化,以及患者对插管的耐受情况。结果:右美托咪定组所有患者镇静满意,均能很好耐受清醒气管插管,插管过程中MAP、HR和SpO2、PETCO2稳定(P>0.05)。咪达唑仑组镇静时有轻度呼吸抑制,插管过程中MAP和HR升高(P<0.05),插管耐受率低于右美托咪定组(P<0.05)。结论:右美托咪定用于清醒气管插管镇静有效,无呼吸抑制,血流动力学稳定,是理想的辅助药。
出处 《实用医学杂志》 CAS 北大核心 2011年第13期2428-2429,共2页 The Journal of Practical Medicine
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