摘要
肺动脉高压是各种原因引起的肺动脉压力持续升高的临床综合征。若缺乏相应的治疗,将导致肺血管重塑。最终发展为右心衰竭,预后极差。但早期诊断及合理治疗可提高该病患者的生存率并改善患者的生存质量。近年.对肺动脉高压发病机制认识的不断深入推动了肺动脉高压治疗手段的发展,现将肺动脉高乐治疗的最新进展综述如下。
Pulmonary arterial hypertension (PAH) is a severe clinical syndrome, which is characlerized by the pcsistant elevated pulmonary artery pressure with various causes. Without the appropriate treatment, it will lead to pulmonary vascular remodeling, and ultimately the development of right heart failure, therefore it is widely regarded as a desease of poor prognosis. However, the early diagnosis and effective treatment can improve the survival rate as well as the quality of life in PAH patients. Recently, the deepening understanding of the pathogenesis of PAH promotes the development of treatment for PAH. The recent progress of the treatment for PAH will be reviewed as follows.
出处
《国际呼吸杂志》
2011年第13期1035-1038,共4页
International Journal of Respiration
关键词
肺动脉高压
靶向治疗
新进展
Pulmonary arterial hypertension
Targeted therapy
Recent progress