非甾体类抗炎药联合他汀类药的肿瘤化学预防作用
摘要
肿瘤的化学预防是通过直接调节基因癌变的某些过程,如预防自由基对DNA损伤、抑制上皮细胞过度增殖或调节上皮细胞分化和凋亡来达到阻止癌变发生的目的。目前有许多化学预防药物正在开发和试验的不同阶段,主要有视黄醇、类胡萝卜素、激素类药物、经典以及非经典抗氧化剂,目前研究比较多的是非甾体抗炎药(NSAIDs)。
出处
《肿瘤预防与治疗》
2011年第4期205-208,共4页
Journal of Cancer Control And Treatment
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