细针穿刺细胞学检查对甲状腺微小乳头状癌的诊断价值

THE VALUE OF FINE-NEEDLE ASPIRATION CYTOLOGY IN THE DIANOSIS OF PAPILLIARY THYROID MICROCARCINOMA

目的探讨B超引导下细针穿刺细胞学(fine-needle aspiration cytology,FNAC)检查在甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)诊断中的应用价值。方法对231例经B超引导下FNAC诊断为PTMC及23例未诊断为恶性结节并行手术治疗患者的临床资料作回顾性分析。结果 254例患者当中术后病例证实为PTMC共230例;术前B超引导下FNAC对PTMC诊断准确率98.03%,特异性87.50%,假阳性率1.30%,假阴性率8.70%;癌灶直径0.20～1.00cm,平均0.64cm。结论 B超引导下FNAC对于PTMC有较高的诊断准确率,能为临床医师术前诊断和治疗提供可靠的依据。

Objective To explore the clinical value of B - mode ultrasonography - guided fine -needle aspiration cytology （FNAC）in the diagnosis of papillary thyroid microcarcinoma （PTMC）. Methods The clinical data of 231 cases with FFMC diagnosed by B -mode uhrasonography -guided FNAC and 23 cases who were not diagnosed as malignant nodule were retrospectively analyzed. Results Among the 254 cases, 230 were FFMC confirmed by post - operative pathology. The accuracy rate, specificity, false positive rate, false negative rate of preoperative B - mode ultrasonography - guided FNAC was 98.03% ,87.50% , 1.30% and 8.70% respectively. The maximum diameter of carcinouma focus was 1.00cm, and the minimum was 0.20cm, mean 0.64cm. Conclusion B - modb uhrasonography - guided FNAC has a high accuracy rate in diagnosing PTMC, and it can offer dependable basis of pre - operative diagnosis and therapy for clinician.