194例HIV阳性孕妇HBV HCV及梅毒合并感染状况分析

Incidence of HBV,HCV and syphilis co-infections among 194 HIV-infected pregnant women

目的了解广西艾滋病病毒(HIV)阳性孕妇合并感染乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、梅毒状况,为医疗部门及相关部门采取有效的措施,实施母婴阻断、提高人口素质提供科学的依据。方法对广西贺州、柳州、南宁和横县发现的194名HIV阳性孕妇的HBV、HCV及梅毒合并感染状况进行检测分析。结果在调查的194名HIV阳性孕妇中,HIV/HCV、HIV/HBV和HIV/梅毒合并感染率分别为14.14%、9.42%和5.24%。2.62%和1.05%的妇女分别有HIV/HBV/HCV和HIV/HCV/梅毒混合感染,吸毒是HIV/HCV合并感染的危险因素,HIV/HBV合并感染存在地区差异。结论研究地区HIV阳性孕妇的HBV、HCV及梅毒感染率显著高于普通孕妇,应早期发现并采取有效的干预措施以预防母婴垂直传播。

Objective To learn about the incidence of HBV,HCV and syphilis co-infections among pregnant women infected with HIV in Guangxi so as to provide scientific evidences for adopting effective interventions to interrupt MTCT and improve quality of the population.Methods The data collected from 194 HIV positive pregnant women in Hezhou,Liuzhou and Nanning cities and Heng county of Guangxi were analyzed.Results Among the 194 HIV-infected pregnant women,the co-infection rates of HIV/HCV,HIV/HBV and HIV/syphilis were 14.14%,9.42% and 5.24%,respectively;2.62% and 1.05% of the women had co-infections of HIV/HBV/HCV and HIV/HCV/ syphilis,respectively.Drug use was the risk factor for HIV/HCV co-infection and the co-infection of HIV/HCB had regional variations.Conclusion The incidence of HBV,HCV and syphilis co-infections in HIV-infected pregnant women are obviously higher than in general pregnant women in the areas under study.It is urgent to detect HIV positive pregnant women at an early stage and take effective interventions for the prevention of vertical mother to child transmission.