特发性血小板减少性紫癜脾切除术后早期并发症

Early postoperative complications of splenectomy for idiopathic thrombocytopenic purpura.

目的 评估脾切除治疗特发性血小板减少性紫癜(ITP) 的安全性。方法 回顾分析了167 例ITP 选择性脾切除术的术后早期并发症。结果 14 例(8-38 % ) 病人出现17 例次术后早期并发症:切口感染7 例,腹腔大出血2 例,颅内出血2 例,膈下脓肿1 例,肺感染1 例,应激性高血糖反应4 例。2 例(1-20 % ) 术后并发颅内出血死亡。结论 选择性脾切除术是ITP 一种安全的治疗手段。

Objective To evaluate the safety of splenectomy for idiopathic thrombocytopenic purpura.Methods Early postoperative complications of 167 elective splenectomy for idiopathic thrombocytopenic purpura(ITP) from June 1986 to May 1999 were retrospectively analyzed.Results The postoperative complication rate was 8.38%(17 complications in 14 patients).This included wound infection(7),intraabdominal bleeding(2),intracranial hemorrhage(2),subphrenic abscess(1),pneumonia(1) and stress diabetes(4).2 patients(1 20%) died of intracranial hemorrhage following operation.Conclusion This study confirms that splenectomy is a safe treatment for ITP.