不全饥饿对大鼠组织中微量元素及金属硫蛋白代谢改变的影响

Effects of semi-starve on the metabolism of trace elements and metallothionein in differen rats tissues

建立不全饥饿大鼠模型，观察其组织中Ｚｎ、Ｃｕ 等微量元素及金属硫蛋白的代谢改变。结果表明：不全饥饿组动物体重及附睾脂肪垫重量明显低于正常组；而肝、肾及脑组织中Ｍ Ｔ 含量显著增高。提示不全饥饿可诱导组织ＭＴ 合成，有利于减轻机体过氧化损伤。

To observe the changes of the contents of Zn,Cu and metallothionein(MT),the semi-starve animal model was made.The results showed that the weight of body and peri-epididymical adipose tissue were both significantly decreased in semi-starve rats,while the MT contents in liver,kidney and brain were significantly increased.It is suggested that MT can be induced by semi-starve stress and the increase of MT contents in beneficial to reducing peroxidation damage.