合并门静脉癌栓的原发性肝癌的化学栓塞治疗

Chemoembolization of primary hepatic carcinoma with portal vein tumor thrombus

对40 例合并门静脉癌栓(PTT) 的原发性肝癌(PHC) 行多次化学栓塞治疗。结果治疗总有效率为67-5 % ,治疗后0-5 ,1 及3 年生存率分别为75-0 % ,12-5 % 及2-5 % ,平均生存期9 月。合并分支PTT 者治疗有效率高于合并其他部位PTT者( P < 0 .05) 。平均治疗间隔期的长短对疗效的影响差异无显著性( P > 0 .05) 。提示在掌握适应症的前提下,TAI+ TAE 是合并PTT 的PHC 的有效治疗方法;不论PTT 分布在何部位,均应积极处理;

Forty cases of primary hepatic carcinoma(PHC) with portal vein tumor thrombus(PTT) underwent chemoembolization twice or more. The total effective rate was 67.5%. The survival rates of half, one, and three years were 75.0%, 12.5%, and 2.5% respectively after the treatment. The mean survival time was 9 months. The effective rate of the cases with the branch PTT was higher than other cases(P<0.05). The influence caused by the average treatment interval had no significant difference(P>0.05). It is suggested that (1) in case of controlling the applications, TAI+TAE is an effective therapy of PHC with PTT; (2) no matter where PTT is, an active management must be adopted; (3) the average treatment interval shall be decided according to conditions of the patients.