院前急救与急诊介入一体化治疗急性脑梗死的临床研究

Clinical study of integration therapy of pre-hospital care and emergency intervention for acute cerebral infarction

目的:观察院前急救与急诊脑动脉内溶栓一体化治疗急性脑梗死的临床疗效,探讨急性脑梗死临床治疗的新模式。方法:采用院前急救与急诊脑动脉内溶栓一体化的治疗模式治疗57例急性脑梗死患者,观察脑血管再通率和患者生存率,采取欧洲卒中量表(ESS)及,Barthel指数(BI),评价患者神经功能的恢复情况。结果:在超早期时间窗内接受溶栓治疗率达91.2%,在3h、6h、12h内接受溶栓治疗的再通率分别为:96.7%、85.7%、60.0%;病死率分别是:0%、4.76%、20.00%;致残率及接近治愈-完全恢复率:0%、9.5%、20.0%;近完全恢复率为:96.8%、85.7%、60.0%。结论:院前急救与急诊脑动脉内溶栓一体化的治疗模式显著缩短了治疗流程,提高了脑血管再通率和神经功能恢复率,值得在临床推广应用。

Objective：To investigate the efficacy and feasibility of integration therapy of pre-hospital care and emergency intervention for acute cerebral infarction treatment.Method：Fifty-seven patients were treated by integration therapy model of emergency intervention and pre-hospital care.Europe stroke scales（ESS） and Barthel Index（BI） were used to evaluate the recovery of neurological function.Result：91.2% patients received thrombolytic therapy within the ultra early time window.The complete recanalization rate was 96.7%,85.7% and 60.0% within 3 hours,6 hours,and 12 hours each by the treated model.The mortality rate was 0%、4.76%、20.00% each and the disability rate was 0%、9.5%、20.0%.The nearly complete recovery rate were 96.8%,85.7%,60.0%.Conclusion：The integration therapy model of pre-hospital care and emergency intervention could shorten the treatment process and improve the rate of vascular recanalization and neurologic recovery.This therapy model is worth of clinical application.