体外反搏治疗冠心病128例临床观察

EECP treatment of clinical observation of 128 cases of coronary heart disease

目的观察体外反搏治疗冠状动脉粥样硬化性心脏病患者的临床疗效。方法将128例确诊冠状动脉粥样硬化性心脏病的患者随机分成两组,两组均给予相似的药物治疗,药物治疗组(A组)仅接受药物治疗;加用体外反搏治疗组(B组)在药物治疗的基础上,每人每天接受体外反搏治疗1次,每次持续1小时,治疗30天,观察入选患者治疗前后24h心绞痛发作的频率、持续时间、行12导联24h动态心电图检查,计算24h内ST段压低的最大幅度及连续压低持续时间的乘积的总和即心肌缺血总负荷(TIB)、检测血清超敏C反应蛋白(hs-CRP)水平。结果治疗30天后,所有患者24h心绞痛发作频率、持续时间、心肌缺血总负荷及血清hs-CRP水平均有所改善,但体外反搏治疗组疗效优于对照组,P<0.05,差异具有统计学意义。结论基础药物联合使用体外反搏治疗冠心病疗效优于单一使用药物治疗。

Objective Observation of External Counterpulsation（ECP） treatment of coronary atherosclerosis in patients with clinical heart disease.Methods 128 patients diagnosed with coronary heart disease were randomly divided into two groups,two groups were given a similar drug treatment,drug treatment group（A group） received only drug therapy;ECP treatment group（B group） with the drug treatment,based on per person per day 1 of ECP treatment,each lasting 1 hour for 30 days,observed the selected patients before and after treatment the frequency of angina pectoris 24h,duration,line 12-lead Holter 24h check,calculate ST segment depression during 24h of the most significant and continuous duration of the product down the sum of the total ischemia burden（TIB）,serum levels of high sensitivity C-reactive protein（hs-CRP）.Results 30 days after treatment,all patients 24h angina attack frequency,duration,total ischemia burden and serum levels of hs-CRP were improved,but the efficacy of EECP treatment group better than the control group,P0.05,difference statistically significant.Conclusion Based combination drug treatment of coronary heart disease using external counterpulsation effective than single drug therapy using.