期刊文献+

不同铁剂疗法用于尿毒症合并肾性贫血的疗效观察 被引量:3

下载PDF
导出
摘要 业已证实,慢性肾脏疾病(CKD)患者随着肾功能的下降,均可出现贫血.贫血可出现在CKD的早期,而至CKD 5期时则非常普遍.促红细胞生成素(EPO)的相对缺乏是肾性贫血的主要原因,自重组红细胞生成素(r-HuEPO)应用于临床,肾性贫血患者的疗效已得到了明显的改善.但临床上也常遇到r-HuEPO治疗效果不佳的患者,因此多位学者逐渐认识到EPO的缺乏并不是导致肾性贫血的唯一原因,许多因素也可致肾性贫血或影响HuEPO的疗效,其中最常见的是铁缺乏.近年来静脉铁剂开始广泛应用于临床,特别是对于绝对铁缺乏的患者KDOQI指南强烈建议使用静脉补铁,国内外文献报道静脉铁剂吸收好、利用率高,其临床疗效越来越得到肯定.蔗糖铁是一种新型的铁剂,目前国内相关的报道较少,笔者通过与口服铁剂的比较评价其疗效,现将结果报道如下.
出处 《浙江医学》 CAS 2011年第6期921-922,共2页 Zhejiang Medical Journal
  • 相关文献

参考文献8

  • 1倪兆慧,钱家麒,丁小强,梅长林,袁伟杰,张金元,陈江华,邢昌赢,刘必成.蔗糖铁注射液治疗维持性血液透析患者肾性贫血的前瞻性、随机对照多中心研究[J].中华肾脏病杂志,2006,22(3):143-148. 被引量:114
  • 2袁群生,郑法雷.静脉应用蔗糖铁纠正功能性缺铁对血液透析患者贫血的作用[J].中国血液净化,2004,3(5):254-260. 被引量:9
  • 3Fishbane S,Kowalski E A,The comparative safety of intravenous iron dextran,iron saecharate,and sodium ferric gluconate[J].Se- minDia1.2000,13:381-384.
  • 4Charytan C,Levin N,Saloum M A. Efficacy and safety of iron su- crose for iron deficiency in patients with dialysis-associated anemia:North American Clinical Trial[J].Am J Kidney Dis,2001,37: 300-307.
  • 5Michael B,Coyne D W, Steven C.Sodium ferric gluconate com-plex in hemodialysis patients:adverse reactions compared to placebo and iron dexan[J].Kidney Int,2002.6 1:1830-1839.
  • 6毕康宁,顾勇,陈文,丁小强,薛骏,戎殳,刘必成,刘文虎,刘蕙兰,张凌,刘子栋,陈旻.静脉注射和口服铁剂治疗肾性贫血的成本效果分析[J].中华肾脏病杂志,2006,22(10):596-600. 被引量:18
  • 7Li H,Wang S X. Intravenous iron sucrose in peritoneal dialysis pa-tients with renal anemia[J].Petit Dial Int,2008,28(2): 149-154.
  • 8Singh T,Reed J,Noble S,et aI.United States Iron Sucrose (Venofer)Clinical Trials Group. Effect of intravenous iron sucrose in peritoneal dialysis patients who receive erythropoiesis-stimu- lating agents for anemia:a randomized,controlled trial[J].Clin J Am SocNephrol,2006,1(3):475-482.

二级参考文献67

  • 1胡善联.药物经济学与药品政策研究[M].昆明:云南科技出版社,1999.110-122.
  • 2[28]Cavill I, Macdougall IC. Erythrepoiesis and iron supply in patients treated with erythropoietin. Erythroppoiesis, 1992, 3:50-55
  • 3[29]Eschbach JW, Cook JD, Finch CA. Iron absorption in chronic renal disease. Clin SCi, 1970, 38:191 - 196
  • 4[30]Gokal R, Millard PR, Weatherall DJ, et al. Iron metabolism in haemodialysis patients. Q J Med, 1979, 48: 369-391
  • 5[31]Donnelly SM, Posen GA, Ali MAM. Oral iron absorption in hemodialysis patients treated with erythropoietin. Clin Invest Med, 1991, 14:271- 276
  • 6[32]Valderrabano F. Erythropoietin in chronic renal failure. Kidney Int,1996, 50: 1373- 1391
  • 7[33]amstra RD, Block MH, Schocker A. Intravenous iron dextran in clinical medicine. JAMA, 1980, 243:1726-1731
  • 8[34]Fishbane S, Ungureanu V, Macsaka JK, et al. Safety of intravenous iron dextran in hemodialysis patients. Am J Kidney Dis, 1996, 28:529- 534
  • 9[35]Faich G, Strobos J. Sodium ferric gluconate complex in sucrose: Safer intravenous iron therapy than iron dextrans. Am J Kidney Dis, 1999,33: 464 - 470
  • 10[36]Lawrence R. Development and comparison of iron dextran products.PDAJ Phar Sci Technol, 1998, 52:190- 197

共引文献129

同被引文献20

引证文献3

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部