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肺表面活性物质预防早产儿呼吸窘迫综合征临床观察 被引量:1

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摘要 目的探讨肺表面活性物质(PS)预防早产儿呼吸窘迫综合征(RDS)的临床效果。方法选取符合条件的60例早产儿随机分成预防组和对照组各30例,预防组给予气管内滴注单剂量PS100 mg/kg,比较两组患儿的RDS发生率、氧疗时间、机械通气时间、住院时间、并发症发生率及病死率。结果预防组早产儿的RDS发生率(16.67%与50.00%)。氧疗时间[(4.3±1.3)天与(13.4±1.8)天]、机械通气时间[(5.3±3.6)天与(9.5±2.4)天]、住院时间[(32.8±3.4)天与(52.8±4.0)天]、并发症发生率(感染:36.7%与86.7%),呼吸暂停(30.0%与83.3%),颅内出血(6.7%与30.0%),气管发育不良(6.7%与26.7%)及病死率(10.0%与43.3%),均比对照组低,两者存在显著性差异(P<0.05)。结论预防性应用PS可降低早产儿RDS发生率及病死率,缩短氧疗时间、机械通气时间和住院天数。
出处 《浙江实用医学》 2011年第3期212-213,共2页 Zhejiang Practical Medicine
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