糖尿病合并脑梗死患者急性期血糖控制水平与神经功能缺损评分的相关分析

The clinical analysis of blood sugar control and NIHSS in acute stage of cerebral infarction with diabetes

目的探讨糖尿病合并脑梗死患者急性期血糖控制水平与神经功能缺损评分的关系。方法对97例糖尿病脑梗死患者资料进行回顾性分析,根据发病后1～7 d空腹血糖控制情况将患者分成3组:血糖控制正常组(Ⅰ组),高血糖1组(Ⅱ组),高血糖2组(Ⅲ组),入院时及治疗2周后均行NIHSS评分,观察了解患者预后。结果 3组患者入院时NIHSS评分无差异(P>0.05),治疗后当急性期空腹血糖水平在6.1 mmol/L以内时,其NIHSS评分与空腹血糖水平在6.1～8.4 mmol/L时,无显著性差异(P>0.05),治疗有效率前者较后者高,二者均与空腹血糖平均水平控制8.4 mmol/L以上组有显著性差异(P<0.01)。结论糖尿病脑梗死患者急性期应积极将血糖控制在8.4mmol/L以内,预后尚可,大于8.4 mmol/L预后差。

Objective To investigate the relationship between the level of blood sugar and NIHSS in acute stage of cerebral infarction with diabetes.Methods Retrospective analysis 97 cases with cerebral infarction combined with diabetes. According to the situation of blood sugar control from 1 to 7 days after cerebral infarction attack,the cases were divided into normal group,high blood sugar group 1 and high blood sugar group 2.The NIHSS scoring were defined at the time points of attack and 2 weeks,and compared the prognosis among groups.Results The NIHSS scoring was not shown difference among 3 groups at the time point of attack（P〉0.05）.There was no significant difference of NIHSS scoring between the level of blood sugar was less than 6.1 mmol/L and 6.1～8.4 mmol/L（P〈0.05）,and the therapeutic effect was better in former group than latter group.There were significant difference between normal,high blood sugar group 1 and high blood sugar group 2（P〈0.01）.Conclusion It suggested that the blood sugar should be controlled within 8.4 mmol/L in acute stage of cerebral infarction with diabetes,the prognosis would be worse once the blood sugar over 8.4 mmol/L.