介入治疗肝海绵状血管瘤的疗效分析

Clinical application of pingyangmycin-lipiodol emulsion embolization to treat cavernous hemangioma of liver

目的评价平阳霉素碘油乳剂肝动脉栓塞对肝海绵状血管瘤的临床疗效。方法于28例肝海绵状血管瘤(CHL)的肝动脉内注入阳霉素碘油乳剂,观察治疗前和治疗后3、6个月时患者临床症状、肿瘤大小的变化以及出现的并发症。观察其栓塞前后肿瘤直径变化、临床症状的缓解和并发症发生情况。结果 PLE栓塞后肿瘤直径明显缩小(P<0.05),术前血管瘤直径平均(8.21±3.33)cm,术后3、6个月血管瘤直径分别平均(4.35±1.22)cm和(2.74±0.73)cm,治疗前有临床症状者治疗后缓解或消失。术后均未出现严重并发症。结论 PLE肝动脉栓塞治疗CHL疗效及安全性良好。

Objective To investigate the therapeutic effects of pingyangmycin-lipiodol emulsion（PLE） embolization to treat cavernous hemangioma of liver（CHL）.Methods 28 patients with CHL were embolized by intra-arterial PLE.The changes of clinic symptoms and tumor volumes,and the occurrence of complications were observed before treatment and at 3,6 months after treatment.Results The tumor diameter significantly decreased after PLE embolization（P0.05）.The mean tumor diameter was（8.21±3.33）cm before intervention,which decreased to（4.35±1.22）cm at 3 months after treatment and to（2.74±0.73）cm at 6 months after treatment.The clinic symptoms were alleviated or even disappeared in all patients.No severe complications occurred during and after the therapy.Conclusion It is suggested that PLE intra-hepatic-arterial embolization is effective and safe for treating CHL.