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S100B与急性缺血性脑损伤 被引量:2

SIOOB and acute ischemic cerebral injury
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摘要 S100B是一类酸性钙结合蛋白,在中枢神经系统中主要存在于胶质细胞,是星形胶质细胞活化的标志之一。S100B可反映胶质细胞的功能,调节神经元与胶质细胞之间复杂的相互作用。近年来的研究显示,S100B蛋白参与了急性缺血性脑损伤的病理学过程,血清S100B蛋白可作为预测脑梗死严重程度、进展以及转归的标记物。 SIOOB is a class of acid calcium-binding protein. It mainly exists in neuroglial cells in the central nervous system, and it is one of the signs of astrocyte activation. SIOOB may reflect the function of neuroglial cells and regulate the complex interactions between the neurons and neuroglial cells. Studies in recent years have demonstrated that SIOOB protein is involved in the pathological processes of acute ischemic brain injury. Serum SIOOB protein can be used as an important marker for identifying the severity of cerebral infarction, progress and outcome.
出处 《国际脑血管病杂志》 北大核心 2011年第6期466-470,共5页 International Journal of Cerebrovascular Diseases
基金 广西科学自然基金(桂科自0832133)
关键词 S100蛋白质类 脑缺血 卒中 生物学标记 S100 proteins Brain ischemia Stroke Biological markers
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二级参考文献54

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