过敏原检测的光化学灭活病毒液态质控物的制备及稳定性观察

Preparation and stability analysis of a photochemistry virus inactivation liquid quality control material for allergens detection

目的制备过敏原检测光化学灭活病毒液体质控物。方法收集外观清晰、无溶血的标本每次测试完后剩余的新鲜血清，用复合保护剂及光化学灭活病毒法制备过敏原检测的液体质控物并观察其稳定性。结果用复合保护剂及光化学灭活病毒法制备过敏原检测的液体质控物与人血清的性状相近，不需复溶，储存时间长，在4～8℃及-20℃的条件下至少可达85周。结论该液体质控物不需复溶，且稳定时间长。

Objective To prepare a stable photochemistry virus inactivation liquid quality control material for allergens detection. Methods Human serum,positive with allergens,was manipulated to prepare the liquid quality control material by being mixed with protectant and treated by photochemistry virus inactivation. Then the stability of it was analyzed. Results The physic properties of prepared liquid quality material were same as human serum, which did not need pretreatment and was stable for more than 85 weeks when being stored at 4--8 ℃ and --20 ℃. Conclusion Liquid quality control material prepared in this research does not need pretreatment and is very stable.