心肌酶与APACHE Ⅱ评分在ICU非心肌梗死患者预后中的价值

The value of myocardium enzyme and APACHE Ⅱ score in the prognosis of ICU patients without AMI

目的探讨心肌酶与APACHEⅡ评分在ICU非心肌梗死(AMI)患者预后中的价值及其相关性。方法从2007年11月至2010年10月入住本院ICU的非AMI患者中随机选取199例,其中存活132例(存活组),死亡67例(死亡组),均于入院时进行APACHEⅡ评分,24 h内常规检测各项心肌酶指标。比较2组患者心肌酶测定结果、APACHEⅡ评分,以及心肌酶各项指标与APACHEⅡ评分的相关性。结果死亡组心肌酶各项指标明显高于存活组,2组间比较差异有统计学意义(P<0.01);存活组APACHEⅡ(12.70±7.85)分,低于死亡组的(24.80±7.46)分,2组间比较差异有统计学意义(P<0.01);心肌酶各项指标与APACHEⅡ评分均呈高度正相关。结论心肌酶和APACHEⅡ评分反映出ICU非AMI患者疾病的严重程度和转归,均可作为评估患者预后的参考指标之一。

Objective To investigate the clinical value of and correlation between myocardium enzymes and APACHE Ⅱ score in the prognosis of intensive care unit（ICU） patients without AMI. Methods During Nov. 2007 to Oct. 2010,199 cases of ICU pa- tients without AMI in our hospital were selected randomly, among which 132 cases survived（survival group）and 67 cases were dead （death group）. APACHE Ⅱ score at admission and myocardium enzymes detection in 24 hours were carried out. The detection resuits of myocardium enzymes and APACHE Ⅱ score were compared between the two groups and the correlation between various myocardiuin enzymes and APACHE Ⅱ was analyzed. Results Serum levels of all myocardium enzymes in the death group were significantly higher than those in the survival group（P〈0.01）. APACHE Ⅱ score of the death group were significantly higher than that of the survival group （P〈 0. 01）. There was fine correlation＂ between various myocardium enzymes and APACHE Ⅱ score. Conclusion Myocardium enzymes and APACHE Ⅱ score can reflect the severity and turnover of the diseases and can be used for the prognosis of the ICU patients without AMI.