期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

2型糖尿病患者经皮氧分压与尿白蛋白肌酐比的相关性研究 被引量：4

The correlationship between urinary albumin creatinine ratio and transcutaneous oxygen pressure in patients with type 2 diabetes mellitus
下载PDF
导出
摘要 目的探讨2型糖尿病(T2DM)患者经皮氧分压(TcPO2)与尿白蛋白肌酐比(ACR)的相关性。方法采用TCM400经皮氧分压检测仪检测360例T2DM患者足背TcPO2值;留取晨尿,采用DCA2000+白蛋白/肌酐分析仪检测尿ACR、留取过夜空腹血检测三酰甘油(TG)、总胆固醇(TC)和血尿酸水平。结果 TcPO2与年龄、病程、吸烟率、高血压、高血脂、血尿酸、尿ACR等因素呈负相关,与性别无相关性。结论异常TcPO2不仅可反映下肢微血管功能状态,还能一定程度提示糖尿病肾脏损害。 Objective To investigate the association between urinary albumin creatinine ratio and Transcutaneous oxygen pressure in patients with type 2 diabetes mellitus.Methods Instep TcPO2 was detected by TCM400 Transcutaneous oxygen pressure in each patient of 360 type 2 diabetics.Urinary albumin creatinine ratio was measured by DCA2000＋ albumin creatinine analyzer.Meanwhile,serum levels of triglyceride,total cholesterol,uric acid in overnight fasting blood speciments were tested.Results TcPO2 was negatively correlated with age,duration,smoke,hypertension,dyslipidemia,elevated blood uric acid,urine ACR,respectively,but not correlated with sex.Conclusion Abnormal TcPO2 may play a warning role not only in early diabetic microvasular dysfunction of lower limb,but also indicate diabetic renal damage.
作者 汝燕 李素梅 张丽 章容
机构地区 安徽医科大学附属省立医院安徽省立医院内分泌科
出处 《中国临床保健杂志》 CAS 2011年第3期258-260,共3页 Chinese Journal of Clinical Healthcare
关键词 糖尿病 2型 血气监测 经皮 白蛋白尿 Diabetes mellitus type 2 Blood gas monitoring transcutaneous Albuminuria
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献10

  • 1Christopher-Stine L, PetriM, Astor BC, et al. Urine protein-to-ereatinine ratio is a reliable measure of proteinuria in lupus nephritis [ J ]. J Rheumatol, 2004,31 ( 8 ) : 1557-1559.
  • 2Bacharach Jbl, Rooke TW, Osmundson PJ, et al. Predictive value of transcutaneous oxygen pressure and amputation success by use of supine and elevation measurements [J]. J Vasc Surg,1992,15(3) :558-563.
  • 3Tonnesen KH. Transcutaneous oxygen tension in imminent foot gangrene[ J]. Aeta Anaesthesiol Scand Suppl, 1978, 68Suppl : 107-110.
  • 4Aronow WS, Ahn C, Weiss MB, et al. Relation of increased hemoglobin A ( 1 c) levels to severity of peripheral arterial disease in patients with diabetes mellitus [ J ]. Am J Cardiol, 2007,99 ( 10 ) : 1468-1469.
  • 5Ceriello A. The possible role of postprandial hyperglycaemia in the pathogenesis of diabetic complications [ J ]. Diabetologia,2003,46suppl : M9-M16.
  • 6Casadei A, Floreani M, Fanolla A, et al. Peripheral arterial disease in a population of type 2 diabetes patients : its correlation with diabetic microangiopathy and laboratory parameters[ J ]. Minerva Cardioangiol, 2003,51 ( 3 ) : 323328.
  • 7Tapp RJ, Shaw JE, de Courten MP, et al. Foot complications in Type 2 diabetes:an Australian population-based study [ J ]. Diabet Med ,2003 ,20 (2) : 105-113.
  • 8Kallio M, Forsblom C, Groop PH, et al. Development of new peripheral arterial occlusive disease in patients with type 2 diabetes during a mean follow-up of 11 years [ J ]. Diabetes Care ,2003,26 (4) : 1241-1245.
  • 9Parving HH, Lewis JB, Ravid M, et al. Prevalence and risk factors for microalbuminuria in a referred cohort of type 2 diabetic patients: a global perspective [ J ]. Kidney Int, 2006,69 ( 11 ) :2057-2063.
  • 10Kawamoto R, Tomita H, Oka Y, et al. Relationship between serum uric acid concentration, metabolic syndrome and carotid atherosclerosis [ J ]. Intern Med,2006,45 (9) : 605-614.

同被引文献44

  • 1郑敏,李春梅,贾冬林.2型糖尿病患者下肢血管病变的超声检查对预防下肢坏疽发生的意义[J].中国临床康复,2004,8(27):5852-5853. 被引量：52
  • 2American diabetes association. Peripheral arterial disease in people with diabetes [ J ]. Diabetes Care, 2003,26 (12) :3333-3341.
  • 3Cimminiello C, Borghi C, Kownator S, et al. Prevalence of peripheral arterial disease in patients at non-high cardio- vascular risk. Rationale and design of the PANDORA study[ J]. BMC Cardiovasc Disord,2010,10 ( 1 ) :35.
  • 4Huttmann SE,Windisch W,Storre JH.Techniques for the measurement and monitoring of carbon dioxide in the blood[J].Ann Am Thorac Soc,2014,11(4):64?-52.
  • 5Rosier S,Launey Y,Bleichner JP,et al.The accuracy of transcutaneous PCO2 in subjects with severe brain injury:A comparison with endtidal PCO2[J].Respir Care,2014,59(8):1242-1247.
  • 6S A,Reading M,Yeomans C,et al.Skin oxygen tension is improved by immersion in oxygen-enriched water[J].International Journal of Cosmetic Science,2013,35(6):600-607.
  • 7VERMA S, BUCHANAN M R, ANDERSON T J. Endothelial function testing as a biomarker of vascular disease [J]. Circu- lation ,2003,108 ( 17 ) :2054-2059.
  • 8PARDO M, ALCARAZ M, BERNAL F L, et al. A solution to ankle-brachial index limitations in peripheral transluminal an- gioplasty [J]. Radiol Med ,2013,118 ( 8 ) : 1373-1378.
  • 9PARDO M, ALCARAZ M, Bernal F L, et al. Transcutaneous oxygen tension measurements following peripheral transluminal angioplasty procedure has more specificity and sensitivity than ankle brachial index[J]. Br J Radiol,2015.88(1046) :20140571.
  • 10郑仁东,任安,陈若平,肖淳纯,陈燕.2型糖尿病患者血管内皮功能的改变[J].中国临床保健杂志,2009,12(2):134-135. 被引量：17

引证文献4

二级引证文献16

中国临床保健杂志
2011年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部