脉搏波传导速度与老年退行性心瓣膜病的相关性研究

Study on pulse wave velocity in patients with senile degenerative heart valvular disease

目的研究脉搏波传导速度(PWV)与老年退行性心瓣膜病(SDHVD)的相关性。方法选择SDHVD患360例作为观察组,再根据瓣膜反流与否分为2个亚组,反流者188例,无反流172例,选择无SDH-VD的同年龄组住院患者150例作为对照组。行PWV检测,比较组两组间PWV值和SDHVD及高血压、高脂血症、冠心病、糖尿病、脑卒中的发生率;比较PWV与瓣膜病变程度的相关性。结果 SDHVD组PWV>对照组,高血压、高脂血症、冠心病、糖尿病、脑卒中的发生率也明显高于对照组(P<0.05);反流组PWV>无反流组(P<0.05),PWV与瓣膜病变严重程度呈正相关。结论 SDHVD患者PWV明显增快,且与瓣膜严重程度呈正相关;PWV在评价SDHVD方面具有一定价值。

Objective To study on pulse wave velocity（PWV） in patients with senile degenerative heart valvular disease（SDHVD）.Methods 360 elderly patients with SDHVD were observed.They were divided in to two groups,188 patients with valvular regurgitation,172 patients with out valvular regurgitation（only degeneracy）,150 subjects without valvular disease were recruited as normal control.Brachial-ankle Pulse wave velocity（BaPWV） were measured among three groups,and relativities were analyzed between BaPWV and the degree of valvular disease.Results PWV was significantly higher in patients with SDHVD than that in people without valvular disease（P〈0.05）;PWV was significantly higher in patients with valvular regurgitation than it in patients without valvular regurgitation（only degeneracy）（P〈0.05）.Conclusions PWV is well correlated with the SDHVD patients.PWV is better index for indicating SDHVD.