膀胱内翻性乳头状瘤36例报告

Inverted urothelial papilloma of the bladder: report of 36 cases

目的提高对膀胱内翻性乳头状瘤(inverted papilloma of the bladder,IPB)的诊治水平。方法回顾分析我科1995年1月至2010年5月收治的具有完整临床和随访结果的36例IPB患者的资料。结果 36例患者均接受手术治疗,其中1例患者同时合并有膀胱尿路上皮细胞癌,1例在内翻性乳头状瘤中合并有尿路上皮细胞癌成分,术后27例行定期膀胱内灌注化疗,9例仅作定期随访,其中1例同时合并有膀胱尿路上皮细胞癌者术后3年复发。结论 IPB是一种预后良好的良性肿瘤,诊断有赖于病理检查,TURBT是治疗该病的标准方法,术后应行膀胱内灌注化疗及定期随访。

Objective To improve the diagnosis and treatment of inverted urothelial papilloma of the bladder.Methods From January 1995 to May 2010,36 patients with urinary inverted urothelial papilloma underwent surgical treatment in our institution were enrolled in this study.Detailed medical records and follow-up data of these patients were reviewed.Results All 36 patients received surgical treatment.One of them was combined with bladder urothelial cancer,and 1 of them was found urothelial cancer within inverted urothelial papilloma.Twenty-seven cases received regular intravesical chemotherapy post-operatively,while 9 patients received regular surveillance.Recurrence was found only in 1 patient who was combined with urothelial cancer.Conclusions Bladder inverted urothelial papilloma is a benign tumor with good prognosis.The diagnosis depends on pathological examination and TURBT is regarded as the golden standard of treatment.Intravesical chemotherapy and regular surveillance should be performed postoperatively.