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酶法测定血清游离脂肪酸的方法学评价及临床应用 被引量:11

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摘要 游离脂肪酸(FFA)是由油酸、软脂酸、亚油酸等组成,是甘油三酯的水解产物,大部分游离脂肪酸与血清白蛋白结合存在于血液中。血清中游离脂肪酸浓度受脂类代谢、糖代谢、内分泌功能等的影响。近年来研究发现FFA水平升高即可增加胰岛素抵抗又可引起高胰岛素血症[1]。
出处 《中国实验诊断学》 北大核心 2011年第6期1099-1101,共3页 Chinese Journal of Laboratory Diagnosis
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参考文献9

  • 1Boden .G, Chen X, Ruzi J, etal. mechanisms of fatty acids induced inhibi- tion of glucose uptake[J]. J Clin Endocrinol Metab, 2001,86: 2153.
  • 2陈江,姜东林,曹利民.2型糖尿病患者血浆抵抗素和游离脂肪酸与胰岛素抵抗关系研究[J].中国微循环,2006,10(1):52-54. 被引量:8
  • 3NCCLS. EP5-A2: Evalution of precision performance of quantitative mea- surement methods; approved guideline-second edition [ S]. Wayne PA, 2004.
  • 4NCCLS. EP7-A2: Interference testing in clinical chemistry; approved guideline-second edition[ S ]. Wayne PA, 2005.
  • 5NCCLS. EP17-A: Protocols for determination of dimits of detection and dimits of duantization; Approved Guideline-Second Edition [ S ]. Wayne PA, 2004.
  • 6NCCLS. EP6-A: Evalution of file linearity of quantitative measurement procedures: A statistical approach; Approved guideline [ S ]. Wayne PA, 2003.
  • 7NCCLS. C28-A2: How to define and determine reference intervals in the clinical laboratory[ S]. Wayne PA, 2000.
  • 8MeGany JD. Banding lecture 2001, Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes[J]. Diabetes,2002,51 ( 1 ) :7.
  • 9李义龙,张延,王萌.肥胖人群的血清游离脂肪酸水平调查[J].中国实验诊断学,2008,12(5):652-654. 被引量:12

二级参考文献10

  • 1米杰,张力.控制代谢综合征关键在预防[J].中华预防医学杂志,2004,38(4):219-220. 被引量:32
  • 2张翼飞,洪洁,顾卫琼,孙首悦,唐金凤,江凌,戴蒙,赵咏桔,宁光.血清游离脂肪酸水平在不同体重指数及糖耐量个体中与胰岛素敏感性及相关指标的关系[J].中华内科杂志,2003,42(11):793-796. 被引量:16
  • 3Haffner SM,Kennedy E,Gonzallez C,et al.A prospective analysis of the HOMA modle [J].The Mexico City Diabetes study.Diabetes Care.1996,19:1138 ~ 1141
  • 4Tritos NA,Mantzoroscs.Syndreme of Severe insulin resistence [J].Clin Endocrinol Metab.1998,83(9):3025 ~3029
  • 5Steppan CM,Bailey ST,Bhat S,et al.The hormone resistin links obesity to diabetes[J].Nature.2001,409:307 ~312
  • 6Santomauro AT, Bodem G, Silva ME, et al. Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects[J]. Diabetes, 1999,48:1836.
  • 7Boden G, Role of fatty acids in the pathogenesis of insulin resistance and NIDDM[J], Diabetes, 1997,46:3.
  • 8Shimabukuro M,Zhou YT, Levi M, Unger RH. Fatty acid- induced cell apoptosis:A link between obesity and diabetes[J]. Proc Natl Acad Sci, 1998,95:2498.
  • 9Unger RH. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: Genetic and clinical implications[ J]. Diabetes, 1995,44 : 863.
  • 10许莉军,张木勋.Resistin与胰岛素抵抗[J].中国微循环,2004,8(1):60-62. 被引量:5

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