摘要
目的:观察采用淋巴细胞对复发性流产进行主动免疫的疗效。方法:58例原因不明复发性流产患者检测封闭抗体阴性后,采用配偶外周血淋巴细胞进行主动免疫治疗。结果:妊娠成功49例,成功率为84.5%;3例未孕(仍在治疗中),2例治疗3次后失访,1例宫外孕,3例流产(其中1例双胎妊娠至6个月流产)。结论:主动免疫对于原因不明复发性流产患者是一种安全、有效的治疗方法,能进一步提高妊娠成功率。
Objective:To observe the effect of lymphocyte immunization therapy for recurrent spontaneous abortion(RSA). Methods: Fifty-eight cases of unexplained RSA detected with negative blocking antibody were treated with peripheral blood lymphocytes from spouse for active immunotherapy. Results:Forty-nine patients (84.5 % ) were pregnanted successfully. Three patients were failed (still in treatment) ,2 cases were lost to follow up after the third treatment, one case was ectopic pregnancy, and 3 cases were aborted (including 1 case of twin pregnancy to six months). Conclusions : Allogeneic immunotherapy on patients with unexplained RSA may be a safe effective treatment,it can furtherly improve the success rate of pregnancy.
出处
《蚌埠医学院学报》
CAS
2011年第6期573-574,共2页
Journal of Bengbu Medical College
关键词
流产
习惯性
免疫
主动
疗效
abortion, habitual
immunity
active
curative effect