VEGF-C、VEGFR-3与恶性肿瘤淋巴结转移关系研究进展
被引量:1
摘要
淋巴结转移是恶性肿瘤一种常见的转移方式。如果能早期发现并阻止这种转移,将有助于改善患者的预后。目前发现新生淋巴管是影响肿瘤转移的一个重要因素,随着对淋巴管标记物和新生淋巴管生长因子研究深入,新生淋巴管与肿瘤转移之间的关系已成为肿瘤转移研究的重点。
出处
《中国实用医药》
2011年第18期243-245,共3页
China Practical Medicine
参考文献11
-
1Oliver G.Lymphatic vasculature development.Nat Rev Immunol,2004,4(1):35-45.
-
2罗景玉,杨长征,李道堂,张百江.非小细胞肺癌组织中VEGFR-3的表达及临床意义[J].中华肿瘤防治杂志,2006,13(15):1178-1179. 被引量:19
-
3Karpanen T,Egeblad M,Karkkainen MJ,et al.Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.Cancer Res,2001,61(5):1786-1790.
-
4Hachisuka T,Narikivo M,Yamada Y,et al.High lymphatatic vessel density cirrelates with density correlates with overexpression of VEGF-C in gastric cancer.Oncol Rep,2005,13(4):733-777.
-
5Furudoi A,Tanaka S,et al.Clininal significance of vescular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma.Oncology,2002,62(2):157-166.
-
6Skobe M,Hawighorst T,Jackson DG,et al.Induction of tumour lymphangiogenesis by VEGF-C promotes breast cancer metastasis.Nat Med,2001,7(2)192-198.
-
7许天文,陈道达,陈剑英,郑勇斌,连彦军.血管内皮生长因子-C在大肠癌中的表达及其与淋巴结转移的关系[J].中华实验外科杂志,2005,22(5):598-600. 被引量:19
-
8牟江洪,阎晓初,李增鹏,王东,段光杰,向德兵,肖华亮,张沁宏.结直肠癌淋巴管生成的特点及其临床病理意义[J].中华病理学杂志,2005,34(6):348-352. 被引量:39
-
9Tanaka T,Ishiguro H.Vascula endothelial growth factor C(VEGF-C)in esoghageal cancer correlates with lymph node metastasis and poor patient prognosis.Journal of Experimental & Clinical Cancer Research,2010,29(1):83.
-
10Shimizu K,Kubo H,Yamaguchi K,et al.Suppression of VEGFR-3 signaling inhibits lymph node metastasis 51 in gastric cancer.Cancer Sci,2004,95(1):328-333.
二级参考文献31
-
1计骏,严超,张俊,于颖彦,张奕,纪玉宝,刘炳亚,朱正纲,尹浩然,林言箴.血管内皮生长因子-C在胃癌中的表达及其与淋巴结转移的关系[J].中华实验外科杂志,2004,21(5):530-532. 被引量:13
-
2王勇杰,刘相萍,沈毅,吕振华,隋爱华,杨堃,王善政.血管内皮生长因子-C及其受体3mRNA在肺癌及癌旁组织中的表达与临床意义[J].中华实验外科杂志,2004,21(11):1322-1323. 被引量:6
-
3武忠弼.病理学[M](第4版)[M].北京:人民卫生出版社,1996.166-173.
-
4Tille JC,Nisato R,Pepper MS.Lymphangiogenesis and tumour metastasis.Novartis Found Symp,2004,256:112-131.
-
5Skobe M,Hawighorst T,Jackson DG.Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis.Nat Med,2001,7:151-152.
-
6Karpanen T,Egeblad M,Karkkainen MJ.Vascular endothelial growth factor-C promotes tumor lymphangiogenesis and intralymphatic tumor growth.Cancer Res,2001,61:1786-1790.
-
7Amilka T,Kitadai Y,Tanaka S,et al.Vascular endothelial growth factor-C expression presicts lymph node metastasis of human gastric carcinomas invading the sub mucosa.Eur J Cancer,2002,38:1413-1419.
-
8Tamura M,Ohta Y.Serum vascular endothelial growth factor-C level in patients with primary nonsmall cell lung carcinoma:a possible diagnostic tool for lymph node metastasis.Cancer,2003,98:1217-1222.
-
9Duff SE,Li C,Jeziorska M,et al.Vascular endothelial growth factors-C and -D and lymphangiogenesis in gastrointestinal tract malignancy.Br J Cancer,2003,89:426-430.
-
10Kawakami M,Furuhata T,Kimura Y,et al.Quantification of vascular endothelial growth factor-C and its receptor-3 messenger RNA with real-time quantitative polymerase chain reaction as a predictor of lymph node metastasis in human colorectal cancer.Surg,2003,133:300-308.
共引文献72
-
1王玲,梁志清,李宇迪.人毛细淋巴管内皮细胞的分离、培养与鉴定[J].实用妇产科杂志,2010,26(3):196-198.
-
2阎晓初,于冬梅,柳凤轩.肿瘤淋巴管生成与肿瘤转移研究进展[J].中华病理学杂志,2005,34(6):370-372. 被引量:22
-
3许天文,陈道达,陈剑英,郑勇斌.大鼠淋巴管内皮细胞的原代培养及鉴定[J].中华实验外科杂志,2006,23(1):105-105.
-
4陈剑雄,许天文,陈剑英.大肠癌中VEGF-C分泌水平的检测及其意义[J].中国普通外科杂志,2006,15(2):116-120. 被引量:2
-
5曹桂明,杨梅.VEGF-C和VEGFR-3对乳腺癌淋巴管生成和淋巴结转移的影响[J].中国肿瘤临床,2006,33(6):310-313. 被引量:16
-
6庞洪刚,李志高,李晓冬,杜杰.核不均一性核糖核蛋白A1在大肠癌中的表达[J].中华实验外科杂志,2006,23(5):599-601. 被引量:1
-
7李锐,高善玲.消化道恶性肿瘤淋巴管生成的研究进展[J].世界华人消化杂志,2006,14(9):894-899. 被引量:3
-
8赫淑倩,张维元.鼻咽癌组织内四种肿瘤相关蛋白表达及其与微血管密度和颈淋巴转移的关系[J].中华耳鼻咽喉头颈外科杂志,2006,41(11):813-817. 被引量:4
-
9达炜,朱金水.淋巴管与消化系恶性肿瘤相关研究[J].国际消化病杂志,2006,26(6):415-417.
-
10刘宝全,张雅芳,马晶,宿菲,李益民,赵玲辉.血管内皮生长因子D和血管内皮生长因子受体3在人结肠癌中的表达及淋巴道转移中的作用[J].解剖学报,2007,38(1):56-60. 被引量:5
同被引文献21
-
1李金平,刘奇伦,吴立刚.不同年龄段乳腺癌临床病理特征分析[J].宁夏医学杂志,2007,29(7):590-592. 被引量:7
-
2Shaw JE, Sicrcc RA,Zimmet PZ, Global cstinates of the prev- alence of diabetes for 2010 and 2030 [ J] , Diabetes Res Clin Pr,2010,87(1) :4 - 14.
-
3Yang YX, Hemessy S, Lewis JD. Type 2 diabetes mellitus and the risk of colorectal cancer[ J]. Clin Gastroenterol Hep- alo1,2005,3 ( 6 ) :587 - 594.
-
4Mills KT, Bellows CF, Hoffman AE, et al. Diabetes mellitus and colorectal cancer prognosis : a meta- analysis [ J ]. Dis Colon Rectum ,2013,56 ( 11 ) : 1304 - 1319.
-
5Opipari A, Liu JR. Glucose deprivation activates AMPK and induces cell death through modulation of akt in ovarian canc- er cells[ J]. Gyncc Oncol,2011,122(2) :389 -395.
-
6Zhou J, Huang W, Tao R, Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells [ J ]. Oncogene, 2009,28 ( 18 ) : 1993 - 2002.
-
7Weinstein D , Simon M, Yehezkel E , et al. Insulin analogues display IGF - I - like mitogenic and antiapoptotic activities in cultured cancer cells[J] . Diabete Metab Res Rev,2009,25 (1):41 -49.
-
8Casa AJ, Dearth R K, Litzenburger BC, et al. The type of 1 insulin -like growth factor receptor pathway:a key player in cancer therapeutic resistance [ J]. Front Biosci, 2008, 13 : 3273 - 3287.
-
9BesserGM,ThomerMO,腾卫平,单忠艳,译.Comprehen-siveClinicalEndoerinology[M].3版.沈阳:辽宁科学技术出版社,2007:293-297.
-
10Joan Fortuny, Yolanda B, Ramon Bosch, et al. Type 2 dia- betes mellitus, its treatment and risk for lymphoma [ J ]. European Journal of Cancer,2005,41 (12) : 1782 - 1787.
二级引证文献3
-
1臧莉,杨继华.2型糖尿病与消化系统恶性肿瘤关系的临床研究[J].现代消化及介入诊疗,2017,22(3):405-407. 被引量:7
-
2孙阳阳.糖尿病与消化系统恶性肿瘤关联的临床研究[J].糖尿病新世界,2018,21(10):39-40.
-
3刘莹,蒋敦科,李素艳,井洁,林瑶光.2型糖尿病合并结肠癌老年患者肿瘤组织中晚期糖基化终产物受体及转化生长因子-β1的表达及临床意义[J].中国老年学杂志,2019,39(6):1334-1337. 被引量:6
-
1邰旭辉,季文樾.淋巴管生成、淋巴管生长因子与肿瘤转移[J].国际耳鼻咽喉头颈外科杂志,2007,31(1):7-9.
-
2陈晰,张建国.VEGF-D及VEGFR-3在乳腺癌淋巴道转移中的作用[J].中国现代普通外科进展,2005,8(2):69-71. 被引量:2
-
3徐岗,王远东,邵中夫,周明.食管鳞状细胞癌组织中埃兹蛋白与淋巴管生长因子表达的意义[J].肿瘤研究与临床,2008,20(2):103-105. 被引量:2
-
4李勇,田卫东.淋巴管——肿瘤治疗的新靶标[J].国外医学(口腔医学分册),2004,31(4):270-272.
-
5陈天星,杨慧,麻新梅.淋巴管生长因子在甲状腺癌中的表达与意义[J].云南医药,2004,25(6):460-463.
-
6王妍,任力.乳腺癌淋巴道转移与肿瘤新生淋巴管关系的研究进展[J].空军医学杂志,2011,27(4):220-221. 被引量:2
-
7关国平,张志勇,冯俊伟,姜莉.趋化生长因子受体-7与结直肠癌淋巴管生成的关系[J].中国老年学杂志,2011,31(14):2619-2621. 被引量:5
-
8赵辉,田兴松.淋巴管生长因子在肿瘤转移中的作用[J].中国现代普通外科进展,2005,8(1):3-5. 被引量:2
-
9李建辉,吕毅,侯东祥,雷霆.淋巴管生长因子对食管鳞癌血管生成、肿瘤转移及预后的影响[J].现代肿瘤医学,2007,15(6):776-779.
-
10武斌,刘陶文.淋巴管生长因子与肿瘤新生淋巴管的研究进展[J].华夏医学,2014,27(1):211-214.