香芹类香料的研制

Preparation of Celery Spices

为制备香芹类香料,以香芹酮为原料,采用锌-醇还原、硼氢化钠还原、乙酸酐酯化等方法合成了二氢香芹酮、二氢香芹醇、乙酸二氢香芹酯。重点研究了锌粉在不同溶剂中的还原效果。目标化合物的结构利用核磁共振、质谱做了确证,该合成路线操作简便,收率高(高于80%),成本低,对工业化生产有一定参考价值。

This paper addressed preparation methods of dihydrocarvone,dihydrocarveol and dihydrocarvyl acetate with carvone as raw material and such steps as reduction,esterification,especially the Zn-ROH reduction.We employed NMR and ESI-MS to determine the structures of these objective compounds.This synthesis process has such positives as low cost and high recovery rate（more than 80%）,and has some references to industrial production.