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他汀类药物干预脑血管疾病的研究进展 被引量:3

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摘要 他汀类(statins)药物是3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂的简称,是新一代高效降脂药,已成为防治心脑血管疾病的必备药物之一。长期以来,学术界一直认为他汀类药物在脑血管疾病预防中的作用机制主要得益于其降脂作用。然而,近年来越来越多的研究证据显示,他汀类药物除了调脂作用外,还具有稳定斑块、改善内皮功能、
出处 《广西中医学院学报》 2011年第2期76-79,共4页 Journal of Guangxi Traditional Chinese Medical University
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参考文献27

  • 1LaRosa J C,Grundy S M,Waters D D,et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease[J]. N Engl J Med,2005,352( 14): 1425-1435.
  • 2Ebrahim S,Sung J,Song Y M,et al. Serum cholesterol, haemorrhagic and ischemic stroke and myocardial infarction: Korean national health service prospective cohort study[J] BMJ,2005(333) :22.
  • 3Amarenco P, Labreuehe J, Lavallee P, et al. Statin in stroke prevention and carotid atheroselerosis:systematie review and met.a-analysis[ J ]. Stroke, 2004(35 ) : 2902-2909.
  • 4Amarenco P. Hypercholesterolemia,lipid-lowering agents, and the risk for brain infarction [J ]. Neurology,2001,57 (Suppl 2) : 35--44.
  • 5Schwartz G G, Olsson A G, Ezekowitz M D, et al. Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes. The MIRACL Study:a randomized con- trolled trial [J]. J Am Med Assoc,2001,285(13) : 1711-1718.
  • 6Crisby M, Nordin-Fredriksson G, Shah P K,et al. Pravastatin treatment increases collagen content and decreases lipid content,inflammation, metalloproteinases, and cell death in human carotid plaques:implications for plaque stabilization. Circulation, 2001 (103) : 926 - 933.
  • 7余昌胤,袁胜山,张骏.辛伐他汀对大鼠脑缺血再灌注后脑组织NOS表达的影响[J].贵州医药,2006,30(12):1069-1071. 被引量:5
  • 8Sakabe K,Fukuda N,Fukuda Y,et al. Comparisons of short and intermediate term effects of pitavastatins versus atorvas- tatin on lipid profiles fibrinolytie parameter and endothelial funetion[J ]. Int J Cardio1,2008,125(1 ) : 136- 138.
  • 9McMurray J J V,Kjekshus J,Gullestad L,et al. Effects of statin therapy according to plasma high-sensitivity C-reac- tive protein concentration in the controlled rosuvastatin multinational trial in heart failure (CORONA).A retrospec- tive analysis[ J ]. Circulation, 2009 (120) : 2188-2194.
  • 10赵水平,吴军,谭利明,胡治平,肖志杰,聂赛,周宏年,蒋波.他汀类药物对急性脑梗死的抗炎作用[J].中华医学杂志,2005,85(40):2841-2845. 被引量:48

二级参考文献98

  • 1周冀英,董为伟.脑梗死患者循环白细胞对内皮细胞金属蛋白酶9表达的影响[J].中华医学杂志,2004,84(12):979-981. 被引量:15
  • 2李红兵,武宝玉,刘微,谢荣荣.调脂治疗对血浆胰岛素水平的影响[J].首都医科大学学报,2005,26(1):87-89. 被引量:2
  • 3谢坤,李勇.他汀类药物多效性研究[J].世界临床药物,2005,26(10):589-591. 被引量:22
  • 4中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量:5233
  • 5范维琥.他汀类药物及其非降脂作用疗效评价[J].临床新视点,2002,(1):9-9.
  • 6宁育.心衰治疗新策略[J].中国医学论坛报,2002,28(41):30-30.
  • 7诸骏仁.调脂治疗的趋势[J].临床新视点,2002,(1):1-2.
  • 8[15]Onolo G, Melis MG, Formato M, Angius MF, Carboni A,Brizzi P, et al. Additive effects of simvastatin beyond its effects on LDL cholesterol in hypertensive type 2 diabetic patients[J].Eur J Clin Invest, 2000;30(11) :980 - 7
  • 9[16]Velussi M, Cernigoi AM, Tortul C, Memi M. Atrovastatin for the management of type-2 diabetic patients with dyslipidemia. A mid-term (9-month) treatment experience [ J]. Diabetes Nutr Metab, 1999; 12(6) :407 - 12
  • 10[17]Sposito AC, Mansur AP, Coelho OR, Nicolau JC, Ramires JA. Additional reduction in blood pressure after cholesterol-lowering treatment by statins (lovastatin or pravastatin) in hypercholesterolemic patients using angiotensin-converting enzyme inhibitors (enalapril or lisinopril)[J]. Am J Cardiol, 1999; 83(10): 1497 - 9

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