人类免疫缺陷病毒感染患者临床特点分析

Analysis on Clinical Features of AIDS Patients

目的观察人类免疫缺陷病毒(HIV)感染后对人体各个系统的影响,为其诊断和治疗提供经验。方法回顾性分析2005年1月～2010年6月于华西医院确诊为HIV感染13例患者的临床表现和相关实验室指标。结果 13例HIV感染患者均合并其他感染,以结核病最为常见;除有T淋巴细胞异常外,多数患者可合并出现血液学异常,包括贫血、白细胞和血小板降低;生化异常,包括球蛋白升高、白蛋白降低;HIV感染患者可合并出现风湿病症状和免疫学异常。结论 HIV感染患者临床表现复杂多样,可合并出现多种感染和风湿病症状,血液学及免疫学异常也比较常见。

Objective To observe the impact of human immunodeficiency virus（HIV） on each system of human body after its infection,in order to provide experiences for diagnosis and treatment of this disease.Methods The clinical manifestations and related laboratory results of 13 inpatients treated in West China Hospital of Sichuan University from January 2005 to June 2010 were reviewed retrospectively.Results The incidence of infection in these patients was 100% with tuberculosis as the most common infection.Apart from the abnormality of T lymphocytes,most patients had a change of hematology and biochemistry,including anemia,depression of leucocytes and platelets,hyperglobulinemia and hypoproteinemia;HIV-infected patients may also presented with rheumatic manifestations or abnormality in the immune system.Conclusion The clinical manifestations of patients with AIDS are complicated.Many kinds of infections and rheumatic manifestations may merge and the change in hematology and immunology is common.