糖尿病性白内障晶状体上皮细胞的电镜观察

Observation of diabetic cataract lens epithelial cells with electron microscope

目的研究糖尿病性白内障晶状体上皮细胞的形态学变化。方法用透射电镜观察对10例糖尿病性白内障及2例正常晶状体上皮细胞的超微结构变化。结果 10例糖尿病性白内障晶状体上皮细胞与正常对照组相比晶体前囊膜晶体上皮细胞间隙增大明显,排列不规则。核变形及线粒体空泡化非常明显,嵴变形扭曲且大量减少或消失,呈现空泡化,内膜和外膜均有破损。结论晶状体上皮细胞的超微结构改变与糖尿病性白内障的发生发展密切相关。

Objective To study the morphological change of the lens epithelial cell in the human diabetic cataract.Methods Ten cases of diabetic cataracts and 2 cases of normal lens epithelial cells of the ultrastructural changes were observed by transmission electron microscope.Results Compared with normal control group,the crystal anterior capsulotomy membrane crystal epithelial cell gap increased obviously and displayed irregularly in 10 cases of diabetic cataract lens epithelial cells.Nuclear deformation and mitochondria vacuoles were apparent,cristae distorted,decreased or even disappear and the inner and outer membranes were damaged.Conclusion There is a close relationship between the change of lens epithelial cells ultrastructure and diabetic cataract occurrence and development.