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多发性骨髓瘤的临床治疗研究新进展 被引量:3

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摘要 随着人口老龄化,多发性骨髓瘤(Multiple Myeloma,MM)发病率正逐年增加,据统计,它占恶性肿瘤1%,血液肿瘤10%,MM以骨髓内浆细胞异常克隆增殖为特征,产生大量单克隆的免疫球蛋白,即M蛋白。欧美国家年发生率是2-5/10万,我国发病率约1/10万,主要集中在老年人,发病年龄50-70a,中位年龄55a,40a以下者少见,男:女=3:1,
出处 《西南军医》 2011年第4期690-693,共4页 Journal of Military Surgeon in Southwest China
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同被引文献21

  • 1张天弼,廖建军.多发性骨髓瘤117例分析[J].中国基层医药,2006,13(6):1018-1019. 被引量:5
  • 2粟小莲.多发性骨髓瘤30例临床分析[J].中国基层医药,2006,13(10):1677-1677. 被引量:1
  • 3侯恩存,王新.恶性肿瘤患者血型变异分析[J].现代肿瘤医学,2006,14(12):1611-1611. 被引量:5
  • 4Bharti AC,Donato N,Aggarwal BB. Curcum in (diferuloymethane)in- hibits constitutive and IL-6-inducible STAT3 phosphorylation in hu- man multiple myeloma cells[J]. J Immuno1,2003,171 (7) : 3863-3871.
  • 5高广义.多发性骨髓瘤32例临床特征分析[J].中国基层医药,2007,14(10):1703-1704. 被引量:3
  • 6Jooeun Bae,Nikhil C,Munshi,et al.Immunotherapy Strategies in Multiple Myeloma.Hematology/Oncology Clinics of North America,2014,28(5):927-943.
  • 7Stevenson JD,Wall C,Patel A,et al.Multiple myeloma:a review.Orthopaedics and Trauma,2014,28(3):187-193.
  • 8Tomer M.Coleman M&M,Ruben Niesvizky.Preclinical and clinical results with pomalidomide in the treatment of relapsed/refractory multiple myeloma.leukemia Research,2014,38(5):517-524.
  • 9Foreman AL,Van de Water J,Gougeon ML,et al.B cells in autoimmune diseases:insights from analyses of immunoglobulin variable(Ig V)gene usage.Autoimmune Rev,2007,6(6):387-401.
  • 10Novaretti MC,Domingues AE,Manhani R,et al.ABO genotping in leukemia patients reveals new ABO variant alleles.Genet Mol Res,2008,7(1):87-94.

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