从影响癌细胞募集能力角度探讨扶正培本治则的抗癌机制

Investigation on the Anticancer Mechanism of the Therapeutic Principle "Fuzheng Peiben" from Cancer Cells' Recruitment Ability

目的:从影响癌细胞募集能力角度探讨扶正培本治则的抗癌机制。方法:将中医扶正培本治则对癌症的认识与现代医学对癌细胞募集能力的研究成果相结合,进而提出新的研究思路。结果:机体的各种细胞及其所具有的生理功能是人体正气的体现,而癌细胞及相关缺氧、炎症状态对正常细胞的招募和驯化能力是癌症进展的主要力量之源,也就是中医所说的"邪"。扶正培本通过抑制或阻断癌细胞及相关缺氧、炎症状态对正常细胞的招募和驯化来抑邪扶正,使正邪达成一种平衡稳态。结论:应从影响癌细胞募集能力角度探讨扶正培本治则的抗癌机制,而不能照搬西方医学致力于清除癌细胞的抗癌研究思路。

Objective：To investigate the anticancer mechanism of the therapeutic principle ＂Fuzheng Peiben＂ from the perspective of impacting cancer cells＇ recruitment ability.Methods：The understanding of cancer from the perspective of TCM therapeutic principle,＂Fuzheng Peiben＂ was combined with research achievements of cancer cells＇ recruitment ability by the modern medicine,and then new research ideas were proposed.Results：The ＂healthy qi＂ of the human body was manifested by a variety of cells and their physiological functions,while the cancer cells and associated hypoxia,inflammation and recruitment and acclimation capacities of normal cells were the main sources of cancer progression,which were called ＂evils＂ in traditional Chinese medicine.＂Fuzheng Peiben＂ could restrain the ＂evils＂ and strengthen the ＂healthy qi＂ through inhibiting or blocking the cancer cells and associated hypoxia,inflammation and the recruitment and acclimation of normal cells in order to strike a balance between the ＂healthy qi＂ and the ＂evils＂.Conclusion：The anticancer mechanism of the therapeutic principle,＂Fuzheng Peiben＂ should be discussed from the angle of impacting the collecting abilities of cancer cells,and should not copy the anticancer research ideas of western medicine which is endeavoring to clear the cancer cells.