摘要
目的探讨米氮平对老年抑郁症的疗效及副反应。方法采用随机分组将76例患者分为米氮平组与帕罗西汀组,治疗8周,用汉密尔顿抑郁量表(HAMD),汉密尔顿焦虑量表(HAMA)评定疗效,用副反应量表(TESS)评定不良反应。结果米氮平组有效率与帕罗西汀组无显著性差异,治愈率及HAMD减分值两组差异有显著性,两组副反应均较轻微。结论米氮平治疗老年抑郁症疗效明显,副反应小。
Objective To explore the efficacy and side effects of Mirtazapine in the treatment of geriatric depression.Methods 76 patients were randomly divided into Mirtazapine group and Paroxetine group for treatment of 8 weeks.The effects and side effects of two groups were evaluated with HAMD,HAMA and TESS.Results The effective rate of Mirtazapine group and Paroxetine group was no statistically significant differencce.There were significant differencce in the cure rate and HAMD score reduced between two group.The side effects of both group were fewer.Conclusion Mirtazapine had a better effect and less side effects drug in the treatment of geriatric depression.
出处
《齐鲁药事》
2011年第6期358-359,共2页
qilu pharmaceutical affairs
关键词
米氮平
帕罗西汀
老年抑郁症
Mirtazapine
Paroxetine
Geriatric depression
